Evidence map›Paper›PMID 23271207›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2013

The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors.

Tracy L Gard, Donald R Hoover, Qiuhu Shi, Mardge H Cohen, Eugene Mutimura, Adebola A Adedimeji, Kathryn Anastos

Open access · greenAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Tracy L GardDepartment of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, USA, tgard@montefiore.org.
Donald R Hoover
Qiuhu Shi
Mardge H Cohen
Eugene Mutimura
Adebola A Adedimeji
Kathryn Anastos
Albert Einstein College of Medicine · USJohn H. Stroger, Jr. Hospital of Cook County · USMontefiore Medical Center · USNew York Medical College · USRutgers, The State University of New Jersey · USUniversity of Global Health Equity · RW

Funding

Women's Interagency HIV Study (WIHS-V)U01AI035004 · NIAID · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI ANASTOS, KATHRYN M., SHARMA, ANJALI · 1993 to 2018
$65.7M
"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8M
Immunology/Pathology CoreP30AI051519 · NIAID · YESHIVA UNIVERSITY · PI GOLDSTEIN, HARRIS · 2003 to 2013
$18.6M
INTERNATIONAL TRAINING IN AIDS/TB PREVENTION RESEARCHD43TW001403 · FIC · YESHIVA UNIVERSITY · PI PRASAD, VINAYAKA R. · 2000 to 2011
$3.8M
METABOLIC EFFECTS OF PROTEASE INHIBITORS IN HIV DISEASER01DK054615 · NIDDK · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MULLIGAN, KATHLEEN · 1998 to 2002
$1.0M
FIC NIH HHS D43 TW001403NIAID NIH HHS P30 AI051519NIAID NIH HHS U01 AI035004NIAID NIH HHS U01 AI096299NIDDK NIH HHS R01 DK054615
6 · The paper itself

Abstract

purposeWe examined whether established associations between HIV disease and HIV disease progression on worse health-related quality of life (HQOL) were applicable to women with severe trauma histories, in this case Rwandan women genocide survivors, the majority of whom were HIV-infected. Additionally, this study attempted to clarify whether post-traumatic stress symptoms were uniquely associated with HQOL or confounded with depression.

methodsThe Rwandan Women's Interassociation Study and Assessment was a longitudinal prospective study of HIV-infected and uninfected women. At study entry, 922 women (705 HIV+ and 217 HIV-) completed measures of symptoms of post-traumatic stress and HQOL as well as other demographic, clinical, and behavioral characteristics.

resultsEven after controlling for potential confounders and mediators, HIV+ women, in particular those with the lowest CD4 counts, scored significantly worse on HQOL and overall quality of life (QOL) than did HIV- women. Even after controlling for depression and HIV disease progression, women with more post-traumatic stress symptoms scored worse on HQOL and overall QOL than women with fewer post-traumatic stress symptoms.

conclusionsThis study demonstrated that post-traumatic stress symptoms were independently associated with HQOL and overall QOL, independent of depression and other confounders or potential mediators. Future research should examine whether the long-term impact of treatment on physical and psychological symptoms of HIV and post-traumatic stress symptoms would generate improvement in HQOL.

Indexed as

AdultCase-Control StudiesCD4 Lymphocyte CountDepressionDisease ProgressionFemaleGenocideHealth Status IndicatorsHIV InfectionsHIV SeronegativityHumansMiddle AgedProspective StudiesPsychiatric Status Rating ScalesQuality of LifeRwanda

Identifiers

PMID23271207
PMCPMC4084826
OpenAlexW2003716971

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.