Evidence map›Paper›PMID 23270319›Full record

Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2013

Efficacy of an eight-week yoga intervention on symptoms of restless legs syndrome (RLS): a pilot study.

Kim E Innes, Terry Kit Selfe, Parul Agarwal, Kimberly Williams, Kathryn L Flack

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Unfolding the role of exercise in the management of sleep disorders.European journal of applied physiology · 2024
    Review
  8. Circadian rhythm in restless legs syndrome.Frontiers in neurology · 2023
    Review
  9. Update on Restless Legs Syndrome: from Mechanisms to Treatment.Current neurology and neuroscience reports · 2019
    Review
  10. Article
  11. Treatment of restless legs syndrome.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2014
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kim E InnesDepartment of Epidemiology, West Virginia University School of Public Health, Morgantown, WV 26506, USA. KInnes@hsc.wvu.edu
Terry Kit Selfe
Parul Agarwal
Kimberly Williams
Kathryn L Flack
West Virginia University · US

Funding

Yoga and Cardiovascular Disease Risk in Older WomenK01AT004108 · NCCIH · WEST VIRGINIA UNIVERSITY · PI INNES, KAREN-KIM E · 2008 to 2012
$632k
NCCIH NIH HHS 1-K01-AT004108NCCIH NIH HHS K01 AT004108
6 · The paper itself

Abstract

backgroundRestless legs syndrome (RLS) is a common and highly burdensome sleep disorder. While relaxation therapies, including yoga, are often recommended for RLS management, rigorous supporting research is sparse. The goal of this preliminary study was to assess the effects of yoga on RLS symptoms and related outcomes in women with RLS.

methodsParticipants were 13 nonsmoking women with moderate to severe RLS, who did not have diabetes, sleep apnea, or other serious concomitant chronic conditions, and who were not pregnant. The intervention was a gentle, 8-week Iyengar yoga program. Core outcomes assessed pre- and post-treatment were RLS symptoms and symptom severity (International RLS Scale [IRLS] and RLS ordinal scale), sleep quality (Medical Outcomes Study Sleep Scale), mood (Profile of Mood States), and perceived stress (Perceived Stress Scale). Participants also completed yoga logs and a brief exit questionnaire regarding their experience with the study.

resultsTen (10) women, aged 32-66 years, completed the study. Participants attended an average 13.4±0.5 (of 16 possible) classes, and completed a mean of 4.1±0.3 (of 5 possible) homework sessions/week. At follow-up, participants demonstrated striking reductions in RLS symptoms and symptom severity, with symptoms decreasing to minimal/mild in all but 1 woman and no participant scoring in the severe range by week 8. Effect sizes (Cohen's d) were large: 1.6 for IRLS total, and 2.2 for RLS ordinal scale. IRLS scores declined significantly with increasing minutes of homework practice per session (r=0.70, p=0.025) and total homework minutes (r=0.64, p<0.05), suggesting a possible dose-response relation. Participants also showed significant improvements in sleep, perceived stress, and mood (all p's≤0.02), with effect sizes ranging from 1.0 to 1.6.

conclusionsThese preliminary findings suggest that yoga may be effective in attenuating RLS symptoms and symptom severity, reducing perceived stress, and improving sleep and mood in women with RLS.

Indexed as

YogaAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedMultivariate AnalysisPilot ProjectsRestless Legs Syndrome

Identifiers

PMID23270319
PMCPMC3673587
OpenAlexW2156777303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.