ArticleBiology letters2013
First evidence for functional vomeronasal 2 receptor genes in primates.
Article in Biology letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 82 citations in OpenAlex.
- First Immunohistochemical Demonstration of the Expression of a Type-2 Vomeronasal Receptor, V2R2, in Wild Canids.International journal of molecular sciences · 2024Article
- Synchronized Expansion and Contraction of Olfactory, Vomeronasal, and Taste Receptor Gene Families in Hystricomorph Rodents.Molecular biology and evolution · 2024Article
- The De-Scent of Sexuality: Did Loss of a Pheromone Signaling Protein Permit the Evolution of Same-Sex Sexual Behavior in Primates?Archives of sexual behavior · 2021Article
- Coding of pheromones by vomeronasal receptors.Cell and tissue research · 2021Review
- Comparative genomic analyses illuminate the distinct evolution of megabats within Chiroptera.DNA research : an international journal for rapid publication of reports on genes and genomes · 2020Article
- Design, delivery and perception of condition-dependent chemical signals in strepsirrhine primates: implications for human olfactory communication.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Evolutionary significance of the variation in acoustic communication of a cryptic nocturnal primate radiation (Ecology and evolution · 2020Article
- First experimental evidence for olfactory species discrimination in two nocturnal primate species (Microcebus lehilahytsara and M. murinus).Scientific reports · 2019Article
- Morphological and histological features of the vomeronasal organ in the brown bear.Journal of anatomy · 2017Article
- Population genetics of mouse lemur vomeronasal receptors: current versus past selection and demographic inference.BMC evolutionary biology · 2017Article
- Baby on board: olfactory cues indicate pregnancy and fetal sex in a non-human primate.Biology letters · 2015Article
- Evolution of spatially coexpressed families of type-2 vomeronasal receptors in rodents.Genome biology and evolution · 2014Article
- Strong links between genomic and anatomical diversity in both mammalian olfactory chemosensory systems.Proceedings. Biological sciences · 2014Article
- The molecular evolutionary dynamics of the vomeronasal receptor (class 1) genes in primates: a gene family on the verge of a functional breakdown.Frontiers in neuroanatomy · 2014Review
- Functional promiscuity in a mammalian chemosensory system: extensive expression of vomeronasal receptors in the main olfactory epithelium of mouse lemurs.Frontiers in neuroanatomy · 2014Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two classes of vomeronasal receptor genes, V1R and V2R, occur in vertebrates. Whereas, V1R loci are found in a wide variety of mammals, including primates, intact V2R genes have thus far only been described in rodents and marsupials. In primates, the V2R repertoire has been considered degenerate. Here, we identify for the first time two intact V2R loci in a strepsirrhine primate, the grey mouse lemur (Microcebus murinus), and demonstrate their expression in the vomeronasal organ. Putatively functional orthologues are present in two other strepsirrhines, whereas, both loci are pseudogenes in a range of anthropoid species. The functional significance of the loci is unknown, but positive selection on one of them is consistent with an adaptive role in pheromone detection. Finally, conservation of V2R loci in strepsirrhines is notable, given their high diversity and role in MUP and MHC detection in rodents.
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