ArticleThe American journal of clinical nutrition2013
Pretreatment dietary patterns, weight status, and head and neck squamous cell carcinoma prognosis.
Article in The American journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Impact of Lifestyle Modifications on Cancer Mortality: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Pooled it
- Pooled it
- The Role of Diet in Prognosis among Cancer Survivors: A Systematic Review and Meta-Analysis of Dietary Patterns and Diet Interventions.Nutrients · 2022Pooled it
- Vegetable and Fruit Consumption and Prognosis Among Cancer Survivors: A Systematic Review and Meta-Analysis of Cohort Studies.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Effect of diet on mortality and cancer recurrence among cancer survivors: a systematic review and meta-analysis of cohort studies.Nutrition reviews · 2016Pooled it
- Pooled it
- Head and neck cancer survivors' preferences for and evaluations of a post-treatment dietary intervention.Nutrition journal · 2019Trial
- Feasibility Outcomes of a Pilot Randomized Clinical Trial to Increase Cruciferous and Green Leafy Vegetable Intake in Posttreatment Head and Neck Cancer Survivors.Journal of the Academy of Nutrition and Dietetics · 2019Trial
- Soy Isoflavone Supplementation Increases Long Interspersed Nucleotide Element-1 (LINE-1) Methylation in Head and Neck Squamous Cell Carcinoma.Nutrition and cancer · 2019Trial
- Blueberry Extract Has Anti-Proliferative Activity in Preclinical Models of Head and Neck Cancer.Head & neck · 2026Article
- Association of Underweight, Sarcopenia, and Cancer Cachexia with Survival Outcomes in Hypopharyngeal Cancer Radiotherapy.Cancers · 2026Article
- Nutrition in head and neck cancer care: a roadmap and call for research.The Lancet. Oncology · 2025Review
- Obesity and overweight in R/R DLBCL patients is associated with a better response to treatment of R2-GDP-GOTEL trial. Potential role of NK CD8 + cells and vitamin D.Cancer & metabolism · 2025Article
- The association between the Mediterranean Diet Score and death from cancer of the head and neck.Cancer causes & control : CCC · 2024Article
- The effect of body mass index at diagnosis on survival of patients with squamous cell head and neck carcinoma.American journal of cancer research · 2024Article
- Nutrition in HNSCC: is it a matter for oncologists? The role of multidisciplinary team-a narrative literature review.Frontiers in oncology · 2024Review
- Association of Body Mass Index With Outcomes Among Patients With Head and Neck Cancer Treated With Chemoradiotherapy.JAMA network open · 2023Observational
- Article
- Systematic Review of Nutrition Interventions to Improve Short Term Outcomes in Head and Neck Cancer Patients.Cancers · 2023Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundFew studies have evaluated the association of diet and weight status with head and neck cancer outcomes.
objectiveThe purpose of this study was to determine whether pretreatment dietary patterns and weight status are associated with head and neck cancer prognosis.
designThis was a longitudinal study of 542 patients with newly diagnosed head and neck cancer who completed food-frequency questionnaires and health surveys before treatment. Clinical data were abstracted from medical records and the Social Security Death Index. Dietary patterns were identified by using principal component analysis. Cox proportional hazard models were used to examine the association of derived dietary patterns (fit by quintiles of exposure) and weight status with time to recurrence and survival, with control for covariates.
resultsDuring the study period, there were 229 deaths and 184 recurrences. Two dietary patterns were identified: a whole-foods pattern (characterized by high intakes of vegetables, fruit, fish, poultry, and whole grains) and a Western pattern (characterized by high intakes of red and processed meats, refined grains, potatoes, and French fries). In multivariable analyses, significantly fewer deaths were observed in subjects most adherent to the whole-foods pattern (HR: 0.56; 95% CI: 0.34, 0.92; P-trend = 0.01). Subjects classified as overweight or obese had significantly fewer deaths (HR: 0.65; 95% CI: 0.49, 0.85; P = 0.001) and recurrences (HR: 0.70; 95% CI: 0.52, 0.95; P = 0.02) than did normal-weight or underweight subjects.
conclusionConsumption of a diet rich in vegetables, fruit, fish, poultry, and whole grains and being overweight before diagnosis with head and neck cancer are associated with a better prognosis.
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