Evidence map›Paper›PMID 23269737›Full record

ArticleJournal of clinical microbiology2013

Mechanisms of linezolid resistance among Staphylococci in a tertiary hospital.

Inmaculada Quiles-Melero, Rosa Gómez-Gil, María Pilar Romero-Gómez, Ana María Sánchez-Díaz, Manuela de Pablos, Julio García-Rodriguez, Avelino Gutiérrez, Jesús Mingorance

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Effect of spdC gene expression on virulence and antibiotic resistance in clinical Staphylococcus aureus isolates.International microbiology : the official journal of the Spanish Society for Microbiology · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Frontiers in microbiology · 2018
    Review
  12. Coagulase-negative staphylococci.Clinical microbiology reviews · 2014
    Review
  13. Molecular epidemiology of coagulase-negative bloodstream isolates: detection of Staphylococcus epidermidis ST2, ST7 and linezolid-resistant ST23.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Inmaculada Quiles-MeleroServicio de Microbiología, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.
Rosa Gómez-Gil
María Pilar Romero-Gómez
Ana María Sánchez-Díaz
Manuela de Pablos
Julio García-Rodriguez
Avelino Gutiérrez
Jesús Mingorance

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms of linezolid resistance among 86 staphylococcal isolates from two intensive care units were investigated. The most frequent was the G2576T mutation in the 23S rRNA (82%). The cfr gene was found in 17% of the isolates, seven S. aureus and eight S. epidermidis isolates. Four of the S. epidermidis isolates had the G2576T mutation and the cfr gene. In four S. haemolyticus isolates, the mechanism could not be identified.

Indexed as

Drug Resistance, BacterialAcetamidesAnti-Bacterial AgentsBacterial ProteinsHumansIntensive Care UnitsLinezolidOxazolidinonesPoint MutationRNA, Ribosomal, 23SStaphylococcal InfectionsStaphylococcus aureusStaphylococcus epidermidisStaphylococcus haemolyticusTertiary Care CentersAcetamidesAnti-Bacterial AgentsBacterial ProteinsCFR protein, Staphylococcus aureusLinezolidOxazolidinonesRNA, Ribosomal, 23S

Identifiers

PMID23269737
PMCPMC3592090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.