ArticleThe World Allergy Organization journal2012
Oxidative stress and antioxidant defense.
Article in The World Allergy Organization journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 1,753 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Tahini Consumption on Oxidative Stress and Inflammation Markers as Well as Endothelial Function and Arterial Stiffness in Healthy Volunteers
Factors Associated With Dermatoporosis
Effect of Tahini Consumption on Oxidative Stress and Inflammation Markers as Well as Endothelial Function and Arterial Stiffness in Patients With Type 2 Diabetes
Who cites it
1,753 citing papers in PubMed, 3 syntheses or guidelines pooled it.
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- Toxicological Effects of Air Pollutants on Human Airway Cell Models Using Air-liquid Interface Systems: A Systematic Review.Current environmental health reports · 2025Pooled it
- The oxidative stress paradigm in arbovirus infections: mechanisms and therapeutic insights.Redox report : communications in free radical research · 2026Review
- Mitigating PM2.5-induced skin injury and aging: botanical strategies targeting redox and inflammatory pathways.Redox report : communications in free radical research · 2026Review
- Synergistic Antibacterial Mechanism of Ginger and Rosemary Essential Oils Against Shewanella putrefaciens.Current microbiology · 2026Article
- Integrated Transcriptomic and Physiological Analyses Reveal Disruption of Digestive Homeostasis Induced by Protease Inhibitors in Anticarsia gemmatalis Caterpillars.Archives of insect biochemistry and physiology · 2026Article
- Citrus depressa peel extract and its polymethoxyflavones mitigate acetaminophen-induced chronic liver injury in mice through antioxidant activation, epigenetic regulation, and gut microbiota modulation.Journal of the science of food and agriculture · 2026Article
- Evaluation of Total Phenols, Flavonoids, and Antioxidant Activity in the Peel and Flesh of Old Apple Cultivars.Foods (Basel, Switzerland) · 2026Article
- Association between sirtuin 1 and markers of oxidative stress in master athletes.European journal of applied physiology · 2026Article
- Chitosan-coated lipid nanocarriers co-delivering curcumin and α-terpinene with enhanced larvicidal activity against Cx. pipiens via oxidative stress.Scientific reports · 2026Article
- Early-life GABA-A receptor blockade with bicuculline attenuates anxiety-like behaviors and cognitive deficits induced by 24-hr sleep deprivation in adult male rats.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Article
- Histopathological, Biochemical and Molecular Investigations on the Potential Endocrine Disruption of Polystyrene Nanoparticles in Adult Male Albino Rats.Environmental toxicology · 2026Article
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- Metformin Enhances Antioxidant Defenses and Limits Lipid Peroxidation Through the Modulation of Nrf2/KEAP1 Pathway in Hippocampal Neurons Exposed to Amyloid-β Oligomers.Neurotoxicity research · 2026Article
- From Ethnobotany to Pharmacology: A Comprehensive Review of Selected Asteraceae Species Highlighting Phytochemical Composition, Traditional Uses, and Diverse Pharmacological Activities.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Machine learning-guided screening and validation of antioxidant small molecules fromFood chemistry: X · 2026Article
- Resveratrol alleviated muscle fiber type transformation in oxidative stressed bovine myotubes through Akt/FoxO signaling pathway.Animal bioscience · 2026Article
1,693 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Reactive oxygen species (ROS) are produced by living organisms as a result of normal cellular metabolism and environmental factors, such as air pollutants or cigarette smoke. ROS are highly reactive molecules and can damage cell structures such as carbohydrates, nucleic acids, lipids, and proteins and alter their functions. The shift in the balance between oxidants and antioxidants in favor of oxidants is termed "oxidative stress." Regulation of reducing and oxidizing (redox) state is critical for cell viability, activation, proliferation, and organ function. Aerobic organisms have integrated antioxidant systems, which include enzymatic and nonenzymatic antioxidants that are usually effective in blocking harmful effects of ROS. However, in pathological conditions, the antioxidant systems can be overwhelmed. Oxidative stress contributes to many pathological conditions and diseases, including cancer, neurological disorders, atherosclerosis, hypertension, ischemia/perfusion, diabetes, acute respiratory distress syndrome, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and asthma. In this review, we summarize the cellular oxidant and antioxidant systems and discuss the cellular effects and mechanisms of the oxidative stress.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.