ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2012
Oral contraceptive misuse as a risk factor for cerebral venous and sinus thrombosis.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Engineering neurovascular thrombosis: Light-based bioprinting for patient-specific modeling and women's cerebrovascular health.Science advances · 2026Review
- Etiological associations of cerebral venous sinus thrombosis among adult sudanese patients: a multicenter cross-sectional study.Annals of medicine and surgery (2012) · 2023Article
- Evaluation of rivaroxaban versus warfarin for the treatment of cerebral vein thrombosis: A case-control blinded study.Current journal of neurology · 2021Article
- Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study.Acta neurologica Belgica · 2020Article
- Unforeseen uses of oral contraceptive pills: Exploratory study in Jordanian community pharmacies.PloS one · 2020Article
- Frequency and characteristics associated with inherited thrombophilia in patients with intracranial dural arteriovenous fistula.Journal of neurosurgery · 2019Article
- Coexistence of High Fibrinogen and Low High-density Lipoprotein Cholesterol Levels Predicts Recurrent Cerebral Venous Thrombosis.Chinese medical journal · 2015Article
- Factor V Leiden, factor V Cambridge, factor II GA20210, and methylenetetrahydrofolate reductase in cerebral venous and sinus thrombosis: A case-control study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Does oral contraceptive pill increase the risk of abnormal Pap smear?Iranian journal of reproductive medicine · 2013Article
- Pulmonary emboli following oral contraceptive misuse and long air travel.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
backgroundConsumption of oral contraceptive pills (OCP) is a known risk factor for cerebral venous and sinus thrombosis (CVST) among women. We determined whether misuse of OCP could increase the risk of CVST in women.
methodsA case-control study was conducted from 2003 to 2007 on 64 female patients with CVST admitted to Al- Zahra medical center and 232 healthy age-matched female OCP users as controls. Patients and controls were interviewed and misuse of OCP was categorized to taking OCP for self-treatment of dysfunctional uterine bleeding, for family planning without physician consult, or for delaying menstruation in purpose of religious customs or traveling, and taking OCP in high dose during the preceding year.
resultsAmong 64 cases and 232 controls, 30 (46.9 %) and 63 (27.2 %), respectively, had a history of OCP misuse (Odds Ratio = 2.36, 95% Confidence Intervals = 1.33 to 4.18, P = 0.002). Also, using cyproterone compound (Diane) was more frequent in the CVST group (P<0.001). Multivariate analysis controlling for age, OCP misuse, type of OCP, and history of coagulopathy showed that OCP misuse (P<0.001) and using Diane as the OCP (P = 0.006) were both independently associated with CVST. DISCUSSION: OCP misuse can be considered as an additional predisposing factor for CVST among women and partly responsible for larger proportion of female patients with CVST. These findings should alarm the healthcare system to create strategies controlling the inappropriate use of OCP among Iranian women.
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23267395PMC3526127W1822833029What OpenQuestion holds
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