ReviewEye & contact lens2013
Microbial keratitis: could contact lens material affect disease pathogenesis?
Review in Eye & contact lens, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Contact Lens-Associated Ocular Surface and Corneal Disorders.Methods and protocols · 2026Review
- Impact of innate immune factors on the persistence of Staphylococcus aureus in the ocular environment.Experimental eye research · 2025Article
- The Role of Biofilms in Contact Lens Associated Fungal Keratitis.Antibiotics (Basel, Switzerland) · 2023Article
- Lipopolysaccharide Enhances Genotoxicity by Activating GADD45G and NF-Oxidative medicine and cellular longevity · 2022Article
- Contact lens use at the time of SARS-CoV-2 pandemic for healthcare workers.The Indian journal of medical research · 2020Article
- Site-specific molecular analysis of the bacteriota on worn spectacles.Scientific reports · 2020Article
- Article
- Mucosal fluid glycoprotein DMBT1 suppresses twitching motility and virulence of the opportunistic pathogen Pseudomonas aeruginosa.PLoS pathogens · 2017Article
- Challenges of corneal infections.Expert review of ophthalmology · 2016Article
- Pseudomonas aeruginosa Survival at Posterior Contact Lens Surfaces after Daily Wear.Optometry and vision science : official publication of the American Academy of Optometry · 2015Article
- Esculentin-1a(1-21)NH2: a frog skin-derived peptide for microbial keratitis.Cellular and molecular life sciences : CMLS · 2015Article
- Clinical Presentation and Antibiotic Susceptibility of Contact Lens Associated Microbial Keratitis.Journal of pathogens · 2015Article
- Clinical Presentation and Microbial Analyses of Contact Lens Keratitis; an Epidemiologic Study.Emergency (Tehran, Iran) · 2014Article
- Antimicrobial compounds in tears.Experimental eye research · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Microbial keratitis is a sight-threatening complication associated with contact lenses. The introduction of silicone hydrogel lens materials with increased oxygen transmission to the ocular surface has not significantly altered the incidence of microbial keratitis. These data suggest that alternate, or additional, predisposing factors involving lens wear must be addressed to reduce or eliminate these infections. The contact lens can provide a surface for microbial growth in situ and can also influence ocular surface homeostasis through effects on the tear fluid and corneal epithelium. Thus, it is intuitive that future contact lens materials could make a significant contribution to preventing microbial keratitis. Design of the "right" material to prevent microbial keratitis requires understanding the effects of current materials on bacterial virulence in the cornea and on ocular surface innate defenses. Current knowledge in each of these areas will be presented with a discussion of future directions needed to understand the influence of lens material on the pathogenesis of microbial keratitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.