ArticleMolecular plant2013
Addressing the role of microRNAs in reprogramming leaf growth during drought stress in Brachypodium distachyon.
Article in Molecular plant, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 92 citations in OpenAlex.
- Non-coding RNAs in plant stress responses: molecular insights and agricultural applications.Plant biotechnology journal · 2025Review
- Characterization of tae-miR156(s) and their response to abiotic stress in wheat (Triticum aestivum L.).BMC plant biology · 2024Article
- Article
- Drought-Induced miRNA Expression Correlated with Heavy Metal, Phenolic Acid, and Protein and Nitrogen Levels in Five Chickpea Genotypes.ACS omega · 2023Article
- Patterns of pan-genome occupancy and gene coexpression under water-deficit in Brachypodium distachyon.Molecular ecology · 2022Article
- Cold-inducible promoter-driven knockdown ofPlant direct · 2022Article
- The Auxin-Response RepressorPlants (Basel, Switzerland) · 2022Article
- Comparative analysis identifies micro-RNA associated with nutrient homeostasis, development and stress response in Arabidopsis thaliana upon high Zn and metal hyperaccumulator Arabidopsis halleri.Physiologia plantarum · 2021Article
- Distinct Evolutionary Profiles and Functions of microRNA156 and microRNA529 in Land Plants.International journal of molecular sciences · 2021Article
- miRNAs play critical roles in response to abiotic stress by modulating cross-talk of phytohormone signaling.Plant cell reports · 2021Review
- A novel plant-fungal association reveals fundamental sRNA and gene expression reprogramming at the onset of symbiosis.BMC biology · 2021Article
- Article
- Comparative Analysis of Transcriptome and sRNAs Expression Patterns in theInternational journal of molecular sciences · 2021Article
- Integrated Analysis of miRNAs Associated With Sugarcane Responses to Low-Potassium Stress.Frontiers in plant science · 2021Article
- Differential Expression of Maize and Teosinte microRNAs under Submergence, Drought, and Alternated Stress.Plants (Basel, Switzerland) · 2020Article
- Characterizing the Role of the miR156-SPL Network in Plant Development and Stress Response.Plants (Basel, Switzerland) · 2020Review
- Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection.Journal of nanobiotechnology · 2019Article
- Small RNA Mobility: Spread of RNA Silencing Effectors and its Effect on Developmental Processes and Stress Adaptation in Plants.International journal of molecular sciences · 2019Review
- Comparative Analysis of miRNA Abundance Revealed the Function of Vvi-miR828 in Fruit Coloring in Root Restriction Cultivation Grapevine (International journal of molecular sciences · 2019Article
- Analysis of microRNAs and their targets from onion (Allium cepa) using genome survey sequences (GSS) and expressed sequence tags (ESTs).Bioinformation · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant responses to drought are regulated by complex genetic and epigenetic networks leading to rapid reprogramming of plant growth. miRNAs have been widely indicated as key players in the regulation of growth and development. The role of miRNAs in drought response was investigated in young leaves of Brachypodium distachyon, a drought-tolerant monocot model species. Adopting an in vivo drought assay, shown to cause a dramatic reduction in leaf size, mostly due to reduced cell expansion, small RNA libraries were produced from proliferating and expanding leaf cells. Next-generation sequencing data were analyzed using an in-house bioinformatics pipeline allowing the identification of 66 annotated miRNA genes and 122 new high confidence predictions greatly expanding the number of known Brachypodium miRNAs. In addition, we identified four TAS3 loci and a large number of siRNA-producing loci that show characteristics suggesting that they may represent young miRNA genes. Most miRNAs showed a high expression level, consistent with their involvement in early leaf development and cell identity. Proliferating and expanding leaf cells respond differently to drought treatment and differential expression analyses suggest novel evidence for an miRNA regulatory network controlling cell division in both normal and stressed conditions and demonstrate that drought triggers a genetic reprogramming of leaf growth in which miRNAs are deeply involved.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.