ArticleJournal of gastrointestinal cancer2013
Body mass index and body surface area and their associations with outcomes in stage II and III colon cancer.
Article in Journal of gastrointestinal cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07255001 (Monitoring Physical Function Changes in Patients With Pancreatic Ductal Adenocarcinoma), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Monitoring Physical Function Changes in Patients With Pancreatic Ductal Adenocarcinoma: Potential for Better Understanding of Treatment Trajectory and Survival
Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Impact of visceral obesity on postoperative outcomes in colorectal cancer: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Body mass index and colorectal cancer prognosis: a systematic review and meta-analysis.Techniques in coloproctology · 2016Pooled it
- Impact of body mass index on surgical outcomes of gastric cancer.BMC cancer · 2018Article
- Revisiting the prognostic relevance of muscle mass among non-metastatic colorectal cancer.Translational gastroenterology and hepatology · 2018Article
- Lifestyle after Colorectal Cancer Diagnosis in Relation to Survival and Recurrence: A Review of the Literature.Current colorectal cancer reports · 2017Review
- Analysis of Body Mass Index and Mortality in Patients With Colorectal Cancer Using Causal Diagrams.JAMA oncology · 2016Observational
- Association between body mass index and mortality for colorectal cancer survivors: overall and by tumor molecular phenotype.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur study aims were to measure the associations between body mass index (BMI) and body surface area (BSA) with outcomes for stage II and III colon cancer and to evaluate if the effect of obesity is modified by disease stage and receipt of adjuvant therapy.
methodsUsing a prospective cohort of stage II and III colon cancer patients who were referred between 2001 and 2005, we compared 3-year relapse-free survival (3-year RFS), 5-year cancer-specific survival (5-year CSS), and 5-year overall survival (5-year OS) rates among different BMI and BSA categories. Cox proportional-hazards models were constructed to explore the relationships between different body compositions and outcomes while adjusting for confounders.
resultsPostoperative height and weight were used to classify 913 patients as normal weight (n = 424, BMI <25 kg/m(2)), overweight (n = 319, BMI 25-30 kg/m(2)), and obese (n = 170, BMI >30 kg/m(2)). Using Mosteller formula, 684 subjects had normal BSA (≤ 2.0 m(2)) and 229 had high BSA (>2.0 m(2)). Obese subjects experienced similar 3-year RFS (61.9 vs. 66.5 vs. 63.6 %, p = 0.51), 5-year CSS (65.6 vs. 72.4 vs. 68.0 %, p = 0.22), and 5-year OS (60.8 vs. 64.0 vs. 62.2 %, p = 0.69) when compared to overweight subjects and those with normal BMIs, respectively. Likewise, individuals with high BSA had similar outcomes as those with normal BSA (66.2 vs. 63.6 %, p = 0.64 for 3-year RFS, 70.3 vs. 68.6 %, p = 0.62 for 5-year CSS, and 64.5 vs. 61.9 %, p = 0.48 for 5-year OS). In Cox models, advanced age, male gender, stage III disease, and poor performance status correlated with inferior RFS, CSS, and OS, but BMI and BSA did not.
conclusionsObesity as measured by either BMI or BSA was not associated with differences in outcomes in stage II and III colon cancer.
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