ReviewWiener medizinische Wochenschrift (1946)2013
Osteoarthritis: histology and pathogenesis.
Review in Wiener medizinische Wochenschrift (1946), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Physical Therapist Management of Glenohumeral Joint Osteoarthritis: A Clinical Practice Guideline from the American Physical Therapy Association.Physical therapy · 2023Guideline
- Article
- Investigating Sex-Linked miRNAs for Potential Osteoarthritis Therapy Biomarkers.International journal of molecular sciences · 2026Article
- Reinforcement of osteochondoral defects repair with leukocyte platelet-rich fibrin and bone marrow-derived mononuclear cells in a rabbit model.BMC musculoskeletal disorders · 2025Article
- VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis.Scientific reports · 2025Article
- The Potential of Intra-Articular Therapies in Managing Knee Osteoarthritis: A Systematic Review.Clinics and practice · 2024Review
- Comprehensive Analysis of Sphingolipid Metabolism-Related Genes in Osteoarthritic Diagnosis and Synovial Immune Dysregulation.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- LncRNA-mediated cartilage homeostasis in osteoarthritis: a narrative review.Frontiers in medicine · 2024Review
- Histopathology of the Intervertebral Disc ofBiology · 2023Article
- Two Amnion-Derived Mesenchymal Stem-Cells Injections to Osteoarthritic Elbows in Dogs-Pilot Study.Animals : an open access journal from MDPI · 2023Article
- Mesenchymal Stromal Cells-Derived Extracellular Vesicles as Potential Treatments for Osteoarthritis.Pharmaceutics · 2023Review
- Automated Prediction of Osteoarthritis Level in Human Osteochondral Tissue Using Histopathological Images.Bioengineering (Basel, Switzerland) · 2023Article
- Histological features of knee osteoarthritis treated with triamcinolone acetonide and hyaluronic acid.Biomedical reports · 2023Article
- Healthy and Osteoarthritis-Affected Joints Facing the Cellular Crosstalk.International journal of molecular sciences · 2023Review
- The epigenetic players and the chromatin marks involved in the articular cartilage during osteoarthritis.Frontiers in physiology · 2023Review
- Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach.Croatian medical journal · 2022Article
- The sirtuin family in health and disease.Signal transduction and targeted therapy · 2022Review
- Chondrocytes In Vitro Systems Allowing Study of OA.International journal of molecular sciences · 2022Review
- Benefits of electroacupuncture and a swimming association when compared with isolated protocols in an osteoarthritis model.Journal of traditional and complementary medicine · 2022Article
- Structural changes in the collagen network of joint tissues in late stages of murine OA.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis is the most common joint disease, affecting over 60 % of the elderly population, leading to incapacity of movement. The primary form is usually oligoarticular. In case of an underlying systemic disease or local injury, the cartilage destruction is considered as secondary osteoarthritis. The pathogenesis of primary osteoarthritis suggests an intrinsic disease of cartilage in which biochemical and metabolic alterations result in its breakdown. Within the last decades, different models were established concentrating on joint structures such as bones or ligaments. Changes of the subchondral bone were found to precede cartilage damage, suggesting a primary alteration of the subchondral region. Other studies concentrated on the metabolic activity of chondrocytes in healthy cartilage of patients with osteoarthritis. The precise event that leads to these changes is still not clear. This review concentrates on the histological features in the course of the disease and provides a summary on different pathogenetic risk factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.