Evidence map›Paper›PMID 23263597›Full record

ArticleJournal of neurology2013

Time trends in incidence of Parkinson's disease diagnosis in UK primary care.

Laura Horsfall, Irene Petersen, Kate Walters, Anette Schrag

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Molecular mirror: reflecting the complexity of Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Update: Descriptive epidemiology of Parkinson disease.Parkinsonism & related disorders · 2024
    Review
  11. The epidemiology of Parkinson's disease.Lancet (London, England) · 2024
    Review
  12. What is the Parkinson Pandemic?Movement disorders : official journal of the Movement Disorder Society · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura HorsfallResearch Department of Primary Care and Population Health, University College London, London, UK.
Irene Petersen
Kate Walters
Anette Schrag

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine time trends and the influence of socio-demographic and geographic factors on incidence of Parkinson's disease (PD) diagnosis in a large UK population-based cohort from The Health Improvement Network (THIN), a UK primary care database. All patients aged over 50 years and contributing data to THIN between January 1999 and December 2009 were extracted and the incidence rates of PD diagnoses were determined by age, gender, time period, social deprivation score and urban/rural status. The overall incidence of PD diagnosis for people over 50 years was 84 per 100,000 person years (95 % CI 82-85). After accounting for socio-demographic factors, the adjusted incidence rates in men were 46 % higher (95 % CI 43-48 %) than in women. Adjusted incidence rates were also 12 % higher in urban than rural areas (95 % CI 4-20 %) and slightly lower in less socially deprived areas. Over time there was a downward trend in PD diagnosis with the adjusted incidence rates declining by around 6 % every calendar year (95 % CI 5-6 %) between 1999 and 2009. Broadening the definition of PD from diagnostic codes to include symptoms and antiparkinsonian drug prescriptions increased the overall incidence to 118 per 100,000 person years (95 % CI 116-120) and showed a much weaker downward trend over time of around 1 % per calendar year (95 % CI 1-2 %). With the broader definition, the adjusted incidence rates remained significantly higher in men compared to women and in urban areas compared with rural areas but not in socially deprived areas. The PD diagnosis rates in the primary care setting were, as expected, higher in men, and slightly higher in urban areas, but not different between socio-economic groups. There was a decline in PD diagnosis in the primary care setting, which may largely represent changes in diagnosis and/or coding rather than a true decline in incidence.

Indexed as

AgedAged, 80 and overAge FactorsFemaleHumansIncidenceMaleMiddle AgedParkinson DiseasePopulation GroupsPrimary Health CareRetrospective StudiesRural PopulationTime FactorsUnited Kingdom

Identifiers

PMID23263597

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.