Evidence map›Paper›PMID 23263585›Full record

ArticleCritical care medicine2013

Deceased organ donation consent rates among racial and ethnic minorities and older potential donors.

David S Goldberg, Scott D Halpern, Peter P Reese

Abstract read
In one paragraph

Article in Critical care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Organ Donation Willingness Among Asian Americans: Results from a National Study.Journal of racial and ethnic health disparities · 2023
    Article
  11. Review
  12. Effect of Policy on Geographic Inequities in Kidney Transplantation.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. A three-tier system for evaluation of organ procurement organizations' willingness to pursue and utilize nonideal donor lungs.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  17. Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David S GoldbergDepartment of Medicine, Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, USA. david.goldberg@uphs.upenn.edu
Scott D Halpern
Peter P Reese
University of Pennsylvania · US

Funding

Measuring and Mitigating Patient Safety Threats Due to Strains on ICU CapacityK08HS018406 · AHRQ · UNIVERSITY OF PENNSYLVANIA · PI HALPERN, SCOTT D · 2009 to 2013
$763k
Measuring Living Kidney Transplantation at Renal Transplant CentersK23DK078688 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI REESE, PETER PHILIP · 2007 to 2011
$658k
Access to Liver Transplantation for Patients with Primary Sclerosing CholangitisF32DK089694 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GOLDBERG, DAVID SETH · 2010 to 2011
$122k
AHRQ HHS K08 HS018406AHRQ HHS K08-HS018406NIDDK NIH HHS F32 DK089694NIDDK NIH HHS F32-DK089694-01NIDDK NIH HHS K23 DK078688NIDDK NIH HHS K23-DK078688-01
6 · The paper itself

Abstract

objectivesWe sought to assess consent rates for organ donation from potential brain-dead donors, and to identify factors associated with variation in consent for donation that could guide the development of targeted interventions to increase organ consent rates. DESIGN, SETTING, AND SUBJECTS: We used data provided by the Organ Procurement and Transplantation Network to analyze the 35,823 organ procurement organization-reported eligible deaths (potential brain-dead donors ≤ 70 yr of age) from January 1, 2008, to October 31, 2011. MEASUREMENTS AND MAIN

resultsExcluding cases where donation authorization was based on prior patient documentation (e.g., donor registry), consent was obtained on 21,601 (68.9%), not obtained on 8,727 (27.8%), and not requested on 1,080 (3.4%) eligible deaths. There were substantial differences in consent rates among racial/ethnic groups (77.0% in whites, 67.5% in Hispanics, 54.9% in blacks, and 48.1% in Asians) and organ procurement organizations (median [interquartile range]: 72.4% [67.5-87.3]). In generalized estimating equation models, with whites and patients ages 18-39 yr as the respective reference groups, consent for donation was less likely to be obtained among Hispanics (odds ratio 0.54; 95% confidence interval 0.44-0.65), blacks (odds ratio 0.35; 95% confidence interval 0.31-0.39), Asians (odds ratio 0.31; 95% confidence interval 0.25-0.37), and eligible donors ages 55-64 (odds ratio 0.72; 95% confidence interval 0.67-0.77), and ≥ 65 yr (odds ratio 0.58; 95% confidence interval 0.52-0.64).

conclusionsIn presenting the first published analyses of consent rates among all eligible deaths, this study confirms smaller and regional studies that showed significant differences in consent rates between whites and racial/ethnic minorities (blacks, Hispanics, and Asians). The study also identifies considerable variation in consent rates between age groups and between organ procurement organizations. Critical care physicians are usually the front-line providers for potential brain-dead donors and their next-of-kin, and these data highlight the need for further research to identify the causes of variation in consent rates and mechanisms to increase rates where appropriate.

Indexed as

AdolescentAdultAgedAge DistributionChildChild, PreschoolDatabases, FactualHumansInfantInfant, NewbornInformed ConsentMiddle AgedRacial GroupsTissue and Organ ProcurementTissue DonorsUnited States

Identifiers

PMID23263585
PMCPMC3557536
OpenAlexW2018212596

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.