ArticleInternational journal of legal medicine2013
Diagnostic value of soluble CD14 subtype (sCD14-ST) presepsin for the postmortem diagnosis of sepsis-related fatalities.
Article in International journal of legal medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Exploration of sepsis assisting parameters in hospital autopsied-patients: a prospective study.Scientific reports · 2023Article
- The sCD14-ST predictive value in the development of adverse outcomes in operated colorectal cancer patients (diagnostic study).Annals of medicine and surgery (2012) · 2023Article
- Post-Mortem Investigations for the Diagnosis of Sepsis: A Review of Literature.Diagnostics (Basel, Switzerland) · 2020Review
- Article
- Sepsis and Nosocomial Infections: The Role of Medico-Legal Experts in Italy.Antibiotics (Basel, Switzerland) · 2019Review
- A Pathophysiological Insight into Sepsis and Its Correlation with Postmortem Diagnosis.Mediators of inflammation · 2016Review
- The accuracy of presepsin for the diagnosis of sepsis from SIRS: a systematic review and meta-analysis.Annals of intensive care · 2015Article
- Postmortem serum protein growth arrest-specific 6 levels in sepsis-related deaths.International journal of legal medicine · 2015Article
- Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU).Wiener klinische Wochenschrift · 2015Article
- Diagnostic accuracy of presepsin (sCD14-ST) for prediction of bacterial infection in cerebrospinal fluid samples from children with suspected bacterial meningitis or ventriculitis.Journal of clinical microbiology · 2015Article
- Expression of CD64 on neutrophils can be used to predict the severity of bloodstream infection before broad range 16S rRNA PCR.Folia microbiologica · 2015Article
- Presepsin (Soluble CD14 Subtype): Reference Ranges of a New Sepsis Marker in Term and Preterm Neonates.PloS one · 2015Observational
- Presepsin (scd14) as a marker of serious bacterial infections in chemotherapy induced severe neutropenia.Iranian journal of pediatrics · 2014Article
- Markers for sepsis diagnosis in the forensic setting: state of the art.Croatian medical journal · 2014Review
- Diagnostic and prognostic value of presepsin in the management of sepsis in the emergency department: a multicenter prospective study.Critical care (London, England) · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The first aim of this study was to assess the diagnostic performance of presepsin (sCD14-ST) in postmortem serum from femoral blood compared to procalcitonin (PCT) to detect sepsis-related fatalities. The second aim was to compare sCD14-ST levels found in postmortem serum to the values in pericardial fluid to investigate the usefulness of the latter as an alternative biological fluid. Two study groups were formed, a sepsis-related fatalities group and a control group. Radiology (unenhanced CT scans and postmortem angiographies), autopsies, histology, neuropathology, and toxicology as well as other postmortem biochemistry investigations were performed in all cases. Microbiological investigations on right cardiac blood were carried out exclusively in septic cases. The results of this study indicated that postmortem serum PCT and sCD14-ST levels, individually considered, allowed septic cases to be identified. Even though increases in both PCT and sCD14-ST concentrations were observed in the control cases, coherent PCT and sCD14-ST results in cases with suspected sepsis allowed the diagnosis to be confirmed. Conversely, no relevant correlation was identified between postmortem serum and pericardial fluid sCD14-ST levels in either the septic or control groups.
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Registered trials
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