Evidence map›Paper›PMID 23262464›Full record

ReviewExercise and sport sciences reviews2013

Are there race-dependent endothelial cell responses to exercise?

Michael D Brown, Deborah L Feairheller

Open access · greenAbstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Systemic FDiversity and equality in health and care · 2017
    Article
  7. Article
  8. Article
  9. Review
  10. Physical activity and the prevention of hypertension.Current hypertension reports · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michael D BrownVascular Health Laboratory, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA. brownmd@temple.edu
Deborah L Feairheller
ECRI Institute · USUniversity of Illinois Chicago · US

Funding

Genetics of In Vivo and In Vitro Endothelial Function in African AmericansR01HL085497 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI BROWN, MICHAEL DAVID · 2007 to 2011
$3.3M
ENOS Genotype, BP, and Exercise in African AmericansK01AG019640 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI BROWN, MICHAEL DAVID · 2003 to 2007
$407k
NHLBI NIH HHS R01 HL085497NIA NIH HHS K01 AG019640NIA NIH HHS KO1 AG019640
6 · The paper itself

Abstract

African Americans have an endothelial dysfunction that likely contributes to their high prevalence of hypertension. Endothelial cell (EC) responses to stimuli could play a role in the development of endothelial dysfunction and hypertension. High physiological levels of vascular laminar shear stress can alter EC phenotype profoundly. It is not known whether there are race-dependent EC responses to laminar shear stress.

Indexed as

Black or African AmericanHealth Status DisparitiesWhite PeopleBiomarkersEndothelial CellsExerciseHumansInflammationNitric OxideNitric Oxide SynthaseOxidative StressStress, PhysiologicalVascular DiseasesBiomarkersNitric OxideNitric Oxide Synthase

Identifiers

PMID23262464
PMCPMC3577070
OpenAlexW2056095442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.