Evidence map›Paper›PMID 23261954›Full record

ReviewSeminars in cell & developmental biology2013

Taste buds as peripheral chemosensory processors.

Stephen D Roper

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 190 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
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  8. Review
  9. Review
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  11. Bitter taste receptors as sensors of gut luminal contents.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Characteristics of A-type voltage-gated KCell and tissue research · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Cortical field maps across human sensory cortex.Frontiers in computational neuroscience · 2023
    Review
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stephen D RoperDepartment of Physiology and Biophysics, and Program in Neuroscience, Miller School of Medicine, University of Miami, 1600 NW 10th Ave., Miami, FL 33136, USA. sroper@med.miami.edu
University of Miami · US

Funding

CHEMOSENSORY TRANSDUCTION IN TASTE CELLSR01DC000374 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROPER, STEPHEN D. · 1989 to 2012
$4.2M
A new method to measure taste bud functionR01DC007630 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROPER, STEPHEN D. · 2006 to 2016
$3.1M
NIDCD NIH HHS 1R01DC007630NIDCD NIH HHS 5R01DC000374NIDCD NIH HHS R01 DC000374NIDCD NIH HHS R01 DC007630
6 · The paper itself

Abstract

Taste buds are peripheral chemosensory organs situated in the oral cavity. Each taste bud consists of a community of 50-100 cells that interact synaptically during gustatory stimulation. At least three distinct cell types are found in mammalian taste buds - Type I cells, Receptor (Type II) cells, and Presynaptic (Type III) cells. Type I cells appear to be glial-like cells. Receptor cells express G protein-coupled taste receptors for sweet, bitter, or umami compounds. Presynaptic cells transduce acid stimuli (sour taste). Cells that sense salt (NaCl) taste have not yet been confidently identified in terms of these cell types. During gustatory stimulation, taste bud cells secrete synaptic, autocrine, and paracrine transmitters. These transmitters include ATP, acetylcholine (ACh), serotonin (5-HT), norepinephrine (NE), and GABA. Glutamate is an efferent transmitter that stimulates Presynaptic cells to release 5-HT. This chapter discusses these transmitters, which cells release them, the postsynaptic targets for the transmitters, and how cell-cell communication shapes taste bud signaling via these transmitters.

Indexed as

AnimalsCell CommunicationHumansReceptors, Cell SurfaceSignal TransductionTaste BudsReceptors, Cell Surface

Identifiers

PMID23261954
PMCPMC3690797
OpenAlexW2003975167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.