ArticleJournal of neuroscience methods2013
Semi-automated method for estimating lesion volumes.
Article in Journal of neuroscience methods, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Multiparametric Ultrasonographic Phenotyping of the Masseter Muscle in Temporomandibular Disorders and Clinically Defined Probable Bruxism.Journal of oral rehabilitation · 2026Article
- Association of posterior occlusal support with ultrasonographic characteristics of the masseter muscle: a prospective single-center study.BMC oral health · 2026Observational
- Deep cerebellar stimulation restores chronic motor deficits and loss of GABAergic neurons following sensorimotor cortex surgical brain injury in female rats.Experimental neurology · 2026Article
- Peripheral B cell populations tune spontaneous neuronal activity in the uninjured hippocampus after stroke.bioRxiv : the preprint server for biology · 2026Article
- Sex-specific cell death mechanisms in rodent sub-acute and chronic stroke.Neuroscience letters · 2025Article
- Orthotopic meningioma rat model exhibits morphological and immunohistochemical congruency and epigenetic concordance with benign primary patient-derived tumors.Scientific reports · 2024Article
- Carry-Over Effect of Deep Cerebellar Stimulation-Mediated Motor Recovery in a Rodent Model of Traumatic Brain Injury.Neurorehabilitation and neural repair · 2024Article
- Injury-Transplantation Interval-Dependent Amelioration of Axonal Degeneration and Motor Deficit in Rats with Penetrating Traumatic Brain Injury.Neurotrauma reports · 2023Article
- Article
- Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury.Bioconjugate chemistry · 2022Article
- Micro-computed tomography utility for estimation of intraparenchymal spinal cord cystic lesions in small animals.Neural regeneration research · 2021Article
- Cellular-resolution monitoring of ischemic stroke pathologies in the rat cortex.Biomedical optics express · 2021Article
- Local delivery of RhoA siRNA by PgP nanocarrier reduces inflammatory response and improves neuronal cell survival in a rat TBI model.Nanomedicine : nanotechnology, biology, and medicine · 2021Article
- Human neural stem cell transplant location-dependent neuroprotection and motor deficit amelioration in rats with penetrating traumatic brain injury.The journal of trauma and acute care surgery · 2020Article
- Differential fracture response to traumatic brain injury suggests dominance of neuroinflammatory response in polytrauma.Scientific reports · 2019Article
- BrdU-induced hyperlocomotion in the stroked rat.Neuroscience letters · 2019Article
- Cellular Changes in Injured Rat Spinal Cord Following Electrical Brainstem Stimulation.Brain sciences · 2019Article
- Lateral Cerebellar Nucleus Stimulation has Selective Effects on Glutamatergic and GABAergic Perilesional Neurogenesis After Cortical Ischemia in the Rodent Model.Neurosurgery · 2018Article
- Crossed Cerebellar Atrophy of the Lateral Cerebellar Nucleus in an Endothelin-1-Induced, Rodent Model of Ischemic Stroke.Frontiers in aging neuroscience · 2017Article
- Volumetry of low-contrast liver lesions with CT: Investigation of estimation uncertainties in a phantom study.Medical physics · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Accurately measuring the volume of tissue damage in experimental lesion models is crucial to adequately control for the extent and location of the lesion, variables that can dramatically bias the outcome of preclinical studies. Many of the current commonly used techniques for this assessment, such as measuring the lesion volume with primitive software macros and plotting the lesion location manually using atlases, are time-consuming and offer limited precision. Here we present an easy to use semi-automated computational method for determining lesion volume and location, designed to increase precision and reduce the manual labor required. We compared this novel method to currently used methods and demonstrate that this tool is comparable or superior to current techniques in terms of precision and has distinct advantages with respect to user interface, labor intensiveness and quality of data presentation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.