Evidence map›Paper›PMID 23261065›Full record

ReviewGastroenterology2013

American Gastroenterological Association technical review on constipation.

Adil E Bharucha, John H Pemberton, G Richard Locke

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 342 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
342citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02633592 nacompletednot on this mapstarted 2014, after this paper: background citation

Seated Evaluation of Anorectal funcTion by High Resolution Anorectal Manometry: a Randomized Comparison of Measurements in the Seated and Left Lateral Positions

TypeinterventionalSponsorUniversity of ZurichRan2014 to 2015Enrolled60ConditionsAnismus, IncontinenceArmsHRARM, MRI Defecography
NCT05687214 nacompletednot on this mapstarted 2022, after this paper: background citation

Investigation on the Effects of an Osteopathic Manipulative Treatment for Constipation in People With Rett Syndrome

TypeinterventionalSponsorAriel UniversityRan2022 to 2023Enrolled12ConditionsRett SyndromeArmsOsteopathic manipulative treatment
NCT07277907 phase3recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation: A Multicenter, Randomized Controlled Trial

TypeinterventionalSponsorThird Military Medical UniversityRan2025 to 2027Enrolled346ConditionsSlow Transit Constipation, PharmacotherapyArmsLubiprostone, Polyethylene glycol (PEG )
3 · Its place in the literature

Who cites it

342 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Meta-analysis of Traditional Chinese Medicine constitution distribution in people with functional constipation.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Pooled it
  3. Pooled it
  4. [Seoul Consensus on Clinical Practice Guidelines for Functional Constipation].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Guideline
  5. Pooled it
  6. Pooled it
  7. Guideline
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Development of a Simple, Point-of-Care Device to Test Anorectal Function in Patients with Constipation: Randomized Clinical Trial.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. High-resolution anorectal manometry profile in patients with chronic constipation versus control.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  18. Article
  19. Article
  20. Article

282 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Adil E BharuchaDivision of Gastroenterology and Hepatology, Mayo Clinic and Mayo Medical School, Rochester, Minnesota, USA.
John H Pemberton
G Richard Locke

Funding

Pathophysiology of Anorectal DisordersR01DK078924 · NIDDK · MAYO CLINIC ROCHESTER · PI BHARUCHA, ADIL E. · 2008 to 2023
$5.0M
NIDDK NIH HHS R01 DK078924NIDDK NIH HHS R01 DK78924
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chronic DiseaseConstipationDefecationHumansRisk Factors

Identifiers

PMID23261065
PMCPMC3531555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.