ArticleEmerging infectious diseases2013
Linezolid dependence in Staphylococcus epidermidis bloodstream isolates.
Article in Emerging infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Clonal dissemination of linezolid-resistantInfection prevention in practice · 2026Article
- Article
- Fierce poison to others: the phenomenon of bacterial dependence on antibiotics.Journal of biomedical science · 2023Review
- Repeated isolation of an antibiotic-dependent and temperature-sensitive mutant of Pseudomonas aeruginosa from a cystic fibrosis patient.The Journal of antimicrobial chemotherapy · 2021Article
- Critical role of tedizolid in the treatment of acute bacterial skin and skin structure infections.Drug design, development and therapy · 2017Review
- Oritavancin Activity Tested against Molecularly Characterized Staphylococci and Enterococci Displaying Elevated Linezolid MIC Results.Antimicrobial agents and chemotherapy · 2016Article
- In vitro activity of tedizolid against linezolid-resistant staphylococci and enterococci.Diagnostic microbiology and infectious disease · 2016Article
- Mutations in the bacterial ribosomal protein l3 and their association with antibiotic resistance.Antimicrobial agents and chemotherapy · 2015Article
- Coagulase-negative staphylococci.Clinical microbiology reviews · 2014Review
- Linezolid-dependent function and structure adaptation of ribosomes in a Staphylococcus epidermidis strain exhibiting linezolid dependence.Antimicrobial agents and chemotherapy · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We document linezolid dependence among 5 highly linezolid-resistant (LRSE) Staphylococcus epidermidis bloodstream isolates that grew substantially faster at 32 µg/mL linezolid presence. These isolates carried the mutations T2504A and C2534T in multiple 23S rRNA copies and 2 mutations leading to relevant amino acid substitutions in L3 protein. Linezolid dependence could account for increasing LRSE emergence.
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Registered trials
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