ReviewCell calcium2013
Ca(2+) homeostasis and regulation of ER Ca(2+) in mammalian oocytes/eggs.
Review in Cell calcium, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Calcium signaling in oocyte quality and functionality and its application.Frontiers in endocrinology · 2024Review
- Comparative effects of a calcium chelator (BAPTA-AM) and melatonin on cryopreservation-induced oxidative stress and damage in ovarian tissue.Scientific reports · 2023Article
- ZneLife · 2023Article
- ZnbioRxiv : the preprint server for biology · 2023Article
- Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8.Developmental cell · 2021Article
- Deletion of TRPV3 and CaV3.2 T-type channels in mice undermines fertility and Ca2+ homeostasis in oocytes and eggs.Journal of cell science · 2021Article
- Maturation conditions, post-ovulatory age, medium pH, and ER stress affect [CaJournal of assisted reproduction and genetics · 2021Article
- Review
- Factors associated with severe sepsis in diarrheal adults and their outcome at an urban hospital, Bangladesh: A retrospective analysis.PloS one · 2021Article
- Dehydroepiandrosterone sulphate (DHEAS) concentrations stringently regulate fertilisation, embryo development and IVF outcomes: are we looking at a potentially compelling 'oocyte-related factor' in oocyte activation?Journal of assisted reproduction and genetics · 2021Article
- The Calcium-Sensing Receptor Is Involved in Follicle-Stimulating Hormone-Induced Cumulus Expansion inFrontiers in cell and developmental biology · 2021Article
- Endoplasmic reticulum stress: New insights into the pathogenesis and treatment of retinal degenerative diseases.Progress in retinal and eye research · 2020Review
- CaCold Spring Harbor perspectives in biology · 2019Review
- Constitutive IPJournal of cell science · 2019Article
- Mitochondrial regulation of [CaCell cycle (Georgetown, Tex.) · 2018Article
- Calcium ion regulation by BAPTA-AM and ruthenium red improved the fertilisation capacity and developmental ability of vitrified bovine oocytes.Scientific reports · 2017Article
- Defective sperm head decondensation undermines the success of ICSI in the bovine.Reproduction (Cambridge, England) · 2017Article
- Store-operated CaCell calcium · 2017Article
- The zinc spark is an inorganic signature of human egg activation.Scientific reports · 2016Article
- Ca(2+) dynamics in oocytes from naturally-aged mice.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The activation of the developmental program in mammalian eggs relies on the initiation at the time of fertilization of repeated rises in the intracellular concentration of free calcium ([Ca(2+)](i)), also known as [Ca(2+)](i) oscillations. The ability to mount the full complement of oscillations is only achieved at the end of oocyte maturation, at the metaphase stage of meiosis II (MII). Over the last decades research has focused on addressing the mechanisms by which the sperm initiates the oscillations and identification of the channels that mediate intracellular Ca(2+) release. This review will describe the up-to-date knowledge of other aspects of Ca(2+) homeostasis in mouse oocytes, such as the mechanisms that transport Ca(2+) out of the cytosol into the endoplasmic reticulum (ER), the Ca(2+) store of the oocyte/egg, into other organelles and also those that extrude Ca(2+). Evidence pointing to channels in the plasma membrane that mediate Ca(2+) entry from the extracellular milieu, which is required for the persistence of the oscillations, is also discussed, along with the modifications that these mechanisms undergo during maturation. Lastly, we highlight areas where additional research is needed to obtain a better understating of the molecules and mechanisms that regulate Ca(2+) homeostasis in this unique Ca(2+) signaling system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.