Trial reportBMC pediatrics2012
Antibiotic surveillance on a paediatric intensive care unit: easy attainable strategy at low costs and resources.
Trial report in BMC pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Quality improvement initiative improves the empiric antibiotic prescribing practices in a tertiary care children's hospital in India.BMJ open quality · 2023Trial
- Impact of COVID-19 on Antimicrobial Stewardship Activities in Hospitalised Children: A Scoping Review.Journal of paediatrics and child health · 2025Article
- Antibiotic Exposure of Critically Ill Children at a Tertiary Care Paediatric Intensive Care Unit in Switzerland.Children (Basel, Switzerland) · 2024Article
- Antibiotic use in pediatric acute care hospitals: an analysis of antibiotic consumption data from Germany, 2013-2020.Infection · 2024Article
- Impact of the COVID-19 Outbreak on the Antibiotic Use Patterns among a Rural Community Population in Eastern China.Antibiotics (Basel, Switzerland) · 2022Article
- Rapid Assay for Sick Children with Acute Lung infection Study (RASCALS): diagnostic cohort study protocol.BMJ open · 2021Article
- Each Additional Day of Antibiotics Is Associated With Lower Gut Anaerobes in Neonatal Intensive Care Unit Patients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review.Antimicrobial resistance and infection control · 2020Article
- Management of early- and late-onset sepsis: results from a survey in 80 German NICUs.Infection · 2019Article
- Evaluation of vancomycin use in university-affiliated hospitals in Southern Khorasan Province (East Iran) based on HICPAC guidelines.Drug, healthcare and patient safety · 2019Article
- Knowledge, Attitude, and Practice with Respect to Antibiotic Use among Chinese Medical Students: A Multicentre Cross-Sectional Study.International journal of environmental research and public health · 2018Article
- Impact of pharmacist-led antibiotic stewardship program in a PICU of low/middle-income country.BMJ open quality · 2018Article
- Evaluation of antibiotic use in Pediatric Intensive Care Unit of a developing country.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016Article
- Medication prescribing checklists and their impact on patient safety: A scoping review.Journal of the American Pharmacists Association : JAPhAArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotic surveillance is mandatory to optimise antibiotic therapy. Our objectives were to evaluate antibiotic use in our pediatric intensive care unit (PICU) and to implement a simple achievable intervention aimed at improving antibiotic therapy.
methodProspective, 3 months surveillance of antibiotic use on PICU (phase I) and evaluation according to the CDC 12-step campaign with development of an attainable intervention. 3 months surveillance (phase II) after implementation of intervention with comparison of antibiotic use.
resultsAppropriate antibiotic use for culture-negative infection-like symptoms and targeted therapy for proven infections were the main areas for potential improvement. The intervention was a mandatory checklist requiring indication and recording likelihood of infection at start of antibiotic therapy and a review of the continuing need for therapy at 48 h and 5 days, reasons for continuation and possible target pathogen. The percentage of appropriate empiric antibiotic therapy courses for culture-negative infection-like symptoms increased from 18% (10/53) to 74% (42/57; p<0.0001), duration of therapy <3 days increased from 18% (10/53) to 35% (20/57; p=0.05) and correct targeting of pathogen increased from 58% (7/12) to 83% (20/24; p=0.21).
conclusionsAntibiotic surveillance using the CDC 12-step campaign can help to evaluate institutional antibiotic therapy. Development of an attainable intervention using a checklist can show improved antibiotic use with minimal expense.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.