ArticleGenome biology2012
cnvHiTSeq: integrative models for high-resolution copy number variation detection and genotyping using population sequencing data.
Article in Genome biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- A Systematic Review of the Advances and New Insights into Copy Number Variations in Plant Genomes.Plants (Basel, Switzerland) · 2025Review
- Current status of structural variation studies in plants.Plant biotechnology journal · 2021Review
- Signatures of TSPAN8 variants associated with human metabolic regulation and diseases.iScience · 2021Article
- Detection of False-Positive Deletions from the Database of Genomic Variants.BioMed research international · 2019Article
- Gene duplication and dosage effects during the early emergence of C4 photosynthesis in the grass genus Alloteropsis.Journal of experimental botany · 2018Article
- iCopyDAV: Integrated platform for copy number variations-Detection, annotation and visualization.PloS one · 2018Article
- Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences.Nature genetics · 2016Review
- Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.American journal of human genetics · 2016Article
- Large multiallelic copy number variations in humans.Nature genetics · 2015Article
- Identification of copy number variants in whole-genome data using Reference Coverage Profiles.Frontiers in genetics · 2015Article
- Whole-genome CNV analysis: advances in computational approaches.Frontiers in genetics · 2015Review
- cnvCapSeq: detecting copy number variation in long-range targeted resequencing data.Nucleic acids research · 2014Article
- cnvOffSeq: detecting intergenic copy number variation using off-target exome sequencing data.Bioinformatics (Oxford, England) · 2014Article
- Common copy number variation detection from multiple sequenced samples.IEEE transactions on bio-medical engineering · 2014Article
- Copy number variation analysis in the context of electronic medical records and large-scale genomics consortium efforts.Frontiers in genetics · 2014Review
- GINDEL: accurate genotype calling of insertions and deletions from low coverage population sequence reads.PloS one · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Recent advances in sequencing technologies provide the means for identifying copy number variation (CNV) at an unprecedented resolution. A single next-generation sequencing experiment offers several features that can be used to detect CNV, yet current methods do not incorporate all available signatures into a unified model. cnvHiTSeq is an integrative probabilistic method for CNV discovery and genotyping that jointly analyzes multiple features at the population level. By combining evidence from complementary sources, cnvHiTSeq achieves high genotyping accuracy and a substantial improvement in CNV detection sensitivity over existing methods, while maintaining a low false discovery rate. cnvHiTSeq is available at http://sourceforge.net/projects/cnvhitseq.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.