ReviewEye (London, England)2013
New clinical pathways for keratoconus.
Review in Eye (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Trial of Simultaneous Combined Transepithelial Photorefractive Keratectomy and Corneal Collagen Cross-linking for Keratoconus
A Prospective, Controlled Study of Refractive Corneal Cross-linking for Progressive Keratoconus
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Pulsed corneal crosslinking in the treatment of Keratoconus: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Corneal collagen cross-linking for treating keratoconus.The Cochrane database of systematic reviews · 2015Pooled it
- Efficacy and safety of deep anterior lamellar keratoplasty vs. penetrating keratoplasty for keratoconus: a meta-analysis.PloS one · 2015Pooled it
- One-Year Efficacy and Safety of Combined Photorefractive Keratectomy and Accelerated Corneal Collagen Cross-Linking after Intacs SK Intracorneal Ring Segment Implantation in Moderate Keratoconus.BioMed research international · 2019Trial
- Demographic and Clinical Characteristics of Patients with Corneal Ectasia at Multiple Medical Centers in Saudi Arabia: A Hospital-based Study.Oman medical journal · 2024Article
- Longitudinal Changes of Cornea Volume Measured by Means of Anterior Segment-Optical Coherence Tomography in Patients with Stable and Progressive Keratoconus.Life (Basel, Switzerland) · 2024Article
- Case Report: Implantable Collamer Lens for Keratoconus with Splinter Cataract.International medical case reports journal · 2024Article
- Splinter Cataract in Patients with Keratoconus and Frequent Eye Rubbing: A Novel Finding.The American journal of case reports · 2023Article
- New Keratoconus Risk Factors: A Cross-Sectional Case-Control Study.Journal of ophthalmology · 2022Article
- Machine Learning Algorithms to Detect Subclinical Keratoconus: Systematic Review.JMIR medical informatics · 2021Review
- A Prospective, Comparative, Clinical Study to Evaluate the Safety and Efficacy of Two Different 0.1% Riboflavin Solutions Used in Collagen Crosslinking Treatment for Patients with Keratoconus.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Outcomes of Corneal Topography among Progressive Keratoconus Patients 12 months following Corneal Collagen Cross-Linking.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- The impact of keratoconus treatment with the Athens Protocol (partial topography-guided photorefractive keratectomy combined with higher-fluence corneal collagen cross-linking) on quality of life: a long-term study.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- An Investigation of the Effects of Riboflavin Concentration on the Efficacy of Corneal Cross-Linking Using an Enzymatic Resistance Model in Porcine Corneas.Investigative ophthalmology & visual science · 2018Article
- Keraring implantation using the Zeiss Visumax femtosecond laser in the management of patients with keratoconus.Eye (London, England) · 2017Article
- Effects of contact lens wearing on keratoconus: a confocal microscopy observation.International journal of ophthalmology · 2017Article
- The influence of the refractive correction on the vision-related quality of life in keratoconus patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Observational
- The Superficial Stromal Scar Formation Mechanism in Keratoconus: A Study Using Laser Scanning In Vivo Confocal Microscopy.BioMed research international · 2016Article
- Evaluation of Intrastromal Riboflavin Concentration in Human Corneas after Three Corneal Cross-Linking Imbibition Procedures: A Pilot Study.Journal of ophthalmology · 2015Article
- Contact lens impact on quality of life in keratoconus patients: rigid gas permeable versus soft silicone-hydrogel keratoconus lenses.International journal of ophthalmology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Pre-2000, the clinical management of keratoconus centred on rigid contact lens fitting when spectacle corrected acuity was no longer adequate, and transplantation where contact lens wear failed. Over the last decade, outcome data have accumulated for new interventions including corneal collagen crosslinking, intracorneal ring implantation, topographic phototherapeutic keratectomy, and phakic intraocular lens implantation. We review the current evidence base for these interventions and their place in new management pathways for keratoconus under two key headings: corneal shape stabilisation and visual rehabilitation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.