Evidence map›Paper›PMID 23257174›Full record

ArticleHeart (British Cardiac Society)2013

Smoking water-pipe, chewing nass and prevalence of heart disease: a cross-sectional analysis of baseline data from the Golestan Cohort Study, Iran.

Farhad Islami, Akram Pourshams, Rajesh Vedanthan, Hossein Poustchi, Farin Kamangar, Asieh Golozar, Arash Etemadi, Hooman Khademi, Neal D Freedman, Shahin Merat and 9 more

Abstract readComparative Study
In one paragraph

Article in Heart (British Cardiac Society), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Waterpipe smoking: a review of pulmonary and health effects.European respiratory review : an official journal of the European Respiratory Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Farhad IslamiOne Gustave L. Levy Place, New York, NY 10029, USA.
Akram Pourshams
Rajesh Vedanthan
Hossein Poustchi
Farin Kamangar
Asieh Golozar
Arash Etemadi
Hooman Khademi
Neal D Freedman
Shahin Merat
Vaani Garg
Valentin Fuster
Jon Wakefield
Sanford M Dawsey
Paul Pharoah
Paul Brennan
Christian C Abnet
Reza Malekzadeh
Paolo Boffetta

Funding

Upper Gastrointestinal Cancer StudiesZIACP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2009 to 2025
$25.6M
Nurse Management of Hypertension in Rural Western KenyaK01TW009218 · FIC · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI VEDANTHAN, RAJESH · 2011 to 2015
$638k
STUDIES OF THE REGULATION OF IGA IMMUNOGLOBULIN SYNTHESISZ01AI000356 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI STROBER, WARREN · 1985 to 1999
–
Cancer Research UK C20/A5860FIC NIH HHS K01 TW009218FIC NIH HHS K01TW009218Intramural NIH HHS ZIA CP000185
6 · The paper itself

Abstract

objectiveWater-pipe and smokeless tobacco use have been associated with several adverse health outcomes. However, little information is available on the association between water-pipe use and heart disease (HD). Therefore, we investigated the association of smoking water-pipe and chewing nass (a mixture of tobacco, lime and ash) with prevalent HD.

designCross-sectional study.

settingBaseline data (collected in 2004-2008) from a prospective population-based study in Golestan Province, Iran.

participants50 045 residents of Golestan (40-75 years old; 42.4% men).

main outcome measuresORs and 95% CIs from multivariate logistic regression models for the association of water-pipe and nass use with HD prevalence.

resultsA total of 3051 (6.1%) participants reported a history of HD, and 525 (1.1%) and 3726 (7.5%) reported ever water-pipe or nass use, respectively. Heavy water-pipe smoking was significantly associated with HD prevalence (highest level of cumulative use vs never use, OR=3.75; 95% CI 1.52 to 9.22; p for trend=0.04). This association persisted when using different cut-off points, when restricting HD to those taking nitrate compound medications, and among never cigarette smokers. There was no significant association between nass use and HD prevalence (highest category of use vs never use, OR=0.91; 95% CI 0.69 to 1.20).

conclusionsOur study suggests a significant association between HD and heavy water-pipe smoking. Although the existing evidence suggesting similar biological consequences of water-pipe and cigarette smoking make this association plausible, results of our study were based on a modest number of water-pipe users and need to be replicated in further studies.

Indexed as

AdultAgedCross-Sectional StudiesFemaleHeart DiseasesHumansIranMaleMasticationMiddle AgedPlant ExtractsPrevalenceProspective StudiesRisk FactorsSmokingTobacco, SmokelessnasPlant Extracts

Identifiers

PMID23257174
PMCPMC3671096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.