ArticleBMC biology2012
No strings attached: new insights into epithelial morphogenesis.
Article in BMC biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Anatomical and molecular insights into avian inner ear sensory hair cell regeneration.Developmental biology · 2025Review
- Apico-basal intercalations enable the integrity of curved epithelia.Computational and structural biotechnology journal · 2025Article
- Architecture of the cortical actomyosin network driving apical constriction in C. elegans.The Journal of cell biology · 2023Article
- Architecture of the cortical actomyosin network driving apical constriction inbioRxiv : the preprint server for biology · 2023Article
- Article
- Mechanical Function of the Nucleus in Force Generation during Epithelial Morphogenesis.Developmental cell · 2019Article
- Membrane trafficking in morphogenesis and planar polarity.Traffic (Copenhagen, Denmark) · 2018Review
- Cellular systems for epithelial invagination.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Invagination of Ectodermal Placodes Is Driven by Cell Intercalation-Mediated Contraction of the Suprabasal Tissue Canopy.PLoS biology · 2016Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
The dramatic ingression of tissue sheets that accompanies many morphogenetic processes, most notably gastrulation, has been largely attributed to contractile circum-apical actomyosin 'purse-strings' in the infolding cells. Recent studies, however, including one in BMC Biology, expose mechanisms that rely less on actomyosin contractility of purse-string bundles and more on dynamics in the global cortical actomyosin network of the cells. These studies illustrate how punctuated actomyosin contractions and flow of these networks can remodel both epithelial and planarly organized mesenchymal sheets.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.