Evidence map›Paper›PMID 23256496›Full record

ReviewNanomedicine (London, England)2013

Nanoparticles for imaging and treating brain cancer.

Joseph D Meyers, Tennyson Doane, Clemens Burda, James P Basilion

Open access · greenAbstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 127 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
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  5. Article
  6. Review
  7. Applications of AuNanomaterials (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Nano-inspired smart medicines targeting brain cancer: diagnosis and treatment.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
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  18. Development of Lomustine andPharmaceutics · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joseph D MeyersDepartments of Biomedical Engineering & Radiology, Case Western Reserve University, Cleveland, OH 44106, USA.
Tennyson Doane
Clemens Burda
James P Basilion
Case Western Reserve University · USNational Foundation for Cancer Research · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Dual-Receptor Targeted Nanoparticles for Photodynamic Therapy of Brain CancerR01EB012099 · NIBIB · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BROOME, ANN-MARIE · 2010 to 2013
$1.3M
NCATS NIH HHS UL1 TR000439NIBIB NIH HHS R01 EB012099
6 · The paper itself

Abstract

Brain cancer tumors cause disruption of the selective properties of vascular endothelia, even causing disruptions in the very selective blood-brain barrier, which are collectively referred to as the blood-brain-tumor barrier. Nanoparticles (NPs) have previously shown great promise in taking advantage of this increased vascular permeability in other cancers, which results in increased accumulation in these cancers over time due to the accompanying loss of an effective lymph system. NPs have therefore attracted increased attention for treating brain cancer. While this research is just beginning, there have been many successes demonstrated thus far in both the laboratory and clinical setting. This review serves to present the reader with an overview of NPs for treating brain cancer and to provide an outlook on what may come in the future. For NPs, just like the blood-brain-tumor barrier, the future is wide open.

Indexed as

NanoparticlesBlood-Brain BarrierBrain NeoplasmsHumans

Identifiers

PMID23256496
PMCPMC3564670
OpenAlexW2133256311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.