ArticlePlant physiology2013
Functional genomics reveals that a compact terpene synthase gene family can account for terpene volatile production in apple.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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63 citing papers in PubMed, 148 citations in OpenAlex.
- Genomic mechanism of aroma terpenoids biosynthesis in plants.Journal of advanced research · 2026Review
- From monthly volatile dynamics to cultivar differences in the aroma of jasmine (Food chemistry: X · 2026Article
- Genome-wide discovery and characterization of terpene synthases contributing to strawberry aroma metabolism.Plant physiology · 2026Article
- Upcycling Discarded Apples into Cider: Yeast and Nutrient Strategies Shaping Fermentation and Sensory Quality.Foods (Basel, Switzerland) · 2026Review
- Evolutionary and molecular insights into the terpene synthase gene (TPS) family in the medicinal plant Bidens alba.Scientific reports · 2026Article
- Welcome Pathogens: Transient Heat Dampens Immune Responses to Acibenzolar-S-Methyl in Apple Plants.Plant, cell & environment · 2026Article
- Genome-wide analysis of terpene synthase family in peanut (Arachis hypogaea L.) explores the potential cross-talk in terpenoid biosynthesis.BMC genomics · 2025Article
- Genomic analysis of terpene synthase family and characterization of ent-kaurene synthase in Chenopodium quinoa.Molecular genetics and genomics : MGG · 2025Article
- Pangenome Identification and Analysis of Terpene Synthase Gene Family Members inInternational journal of molecular sciences · 2024Article
- Comparative transcriptome profiling reveals distinct regulatory responses of secondary defensive metabolism inEcology and evolution · 2024Article
- The Capsicum terpenoid biosynthetic module is affected by spider-mite herbivory.Plant molecular biology · 2023Article
- A geraniol synthase regulates plant defense via alternative splicing in tea plants.Horticulture research · 2023Article
- Transcription factors TgbHLH95 and TgbZIP44 cotarget terpene biosynthesis gene TgGPPS in Torreya grandis nuts.Plant physiology · 2023Article
- Comparative Analysis and Identification of Terpene Synthase Genes inPlants (Basel, Switzerland) · 2023Article
- Genome-wide identification and expression analysis of terpene synthases in Gossypium species in response to gossypol biosynthesis.Functional & integrative genomics · 2023Article
- The terpene synthase (TPS) gene family in kiwifruit shows high functional redundancy and a subset of TPS likely fulfil overlapping functions in fruit flavour, floral bouquet and defence.Molecular horticulture · 2023Article
- Functional Characterization of a (International journal of molecular sciences · 2023Article
- Transcriptome sequencing and gas chromatography-mass spectrometry analyses provide insights into β-caryophyllene biosynthesis inFood chemistry. Molecular sciences · 2022Article
- Article
- Highly efficient biosynthesis of β-caryophyllene with a new sesquiterpene synthase from tobacco.Biotechnology for biofuels and bioproducts · 2022Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Terpenes are specialized plant metabolites that act as attractants to pollinators and as defensive compounds against pathogens and herbivores, but they also play an important role in determining the quality of horticultural food products. We show that the genome of cultivated apple (Malus domestica) contains 55 putative terpene synthase (TPS) genes, of which only 10 are predicted to be functional. This low number of predicted functional TPS genes compared with other plant species was supported by the identification of only eight potentially functional TPS enzymes in apple 'Royal Gala' expressed sequence tag databases, including the previously characterized apple (E,E)-α-farnesene synthase. In planta functional characterization of these TPS enzymes showed that they could account for the majority of terpene volatiles produced in cv Royal Gala, including the sesquiterpenes germacrene-D and (E)-β-caryophyllene, the monoterpenes linalool and α-pinene, and the homoterpene (E)-4,8-dimethyl-1,3,7-nonatriene. Relative expression analysis of the TPS genes indicated that floral and vegetative tissues were the primary sites of terpene production in cv Royal Gala. However, production of cv Royal Gala floral-specific terpenes and TPS genes was observed in the fruit of some heritage apple cultivars. Our results suggest that the apple TPS gene family has been shaped by a combination of ancestral and more recent genome-wide duplication events. The relatively small number of functional enzymes suggests that the remaining terpenes produced in floral and vegetative and fruit tissues are maintained under a positive selective pressure, while the small number of terpenes found in the fruit of modern cultivars may be related to commercial breeding strategies.
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