Evidence map›Paper›PMID 23255793›Full record

ArticleJournal of virology2013

Negevirus: a proposed new taxon of insect-specific viruses with wide geographic distribution.

Nikos Vasilakis, Naomi L Forrester, Gustavo Palacios, Farooq Nasar, Nazir Savji, Shannan L Rossi, Hilda Guzman, Thomas G Wood, Vsevolod Popov, Rodion Gorchakov and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.

  1. Pooled it
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  7. Proteomics analysis of soluble secreted proteins ofFrontiers in cellular and infection microbiology · 2025
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58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Nikos VasilakisCenter for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Naomi L Forrester
Gustavo Palacios
Farooq Nasar
Nazir Savji
Shannan L Rossi
Hilda Guzman
Thomas G Wood
Vsevolod Popov
Rodion Gorchakov
Ana Vázquez González
Andrew D Haddow
Douglas M Watts
Amelia P A Travassos da Rosa
Scott C Weaver
W Ian Lipkin
Robert B Tesh
The University of Texas Medical Branch at Galveston · USColumbia University · USInstituto de Salud Carlos III · ESThe University of Texas at El Paso · US

Funding

NIAID NIH HHS AI157158NIAID NIH HHS HHSN272201000040IPHS HHS HHSN272201000040I/HHSN27200004/D04
6 · The paper itself

Abstract

Six novel insect-specific viruses, isolated from mosquitoes and phlebotomine sand flies collected in Brazil, Peru, the United States, Ivory Coast, Israel, and Indonesia, are described. Their genomes consist of single-stranded, positive-sense RNAs with poly(A) tails. By electron microscopy, the virions appear as spherical particles with diameters of ∼45 to 55 nm. Based on their genome organization and phylogenetic relationship, the six viruses, designated Negev, Ngewotan, Piura, Loreto, Dezidougou, and Santana, appear to form a new taxon, tentatively designated Negevirus. Their closest but still distant relatives are citrus leposis virus C (CiLV-C) and viruses in the genus Cilevirus, which are mite-transmitted plant viruses. The negeviruses replicate rapidly and to high titer (up to 10(10) PFU/ml) in mosquito cells, producing extensive cytopathic effect and plaques, but they do not appear to replicate in mammalian cells or mice. A discussion follows on their possible biological significance and effect on mosquito vector competence for arboviruses.

Indexed as

AnimalsAnophelesBase SequenceCell LineChlorocebus aethiopsCricetinaeCulexDrosophila melanogasterInsect VirusesPhlebotomusPhylogenyRNA, ViralRNA VirusesSequence Analysis, RNAVero CellsVirus ReplicationRNA, Viral

Identifiers

PMID23255793
PMCPMC3571365
OpenAlexW2154936936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.