Evidence map›Paper›PMID 23255219›Full record

ReviewPediatric blood & cancer2013

Children's Oncology Group's 2013 blueprint for research: rare tumors.

Carlos Rodriguez-Galindo, Mark Krailo, Lindsay Frazier, Murali Chintagumpala, James Amatruda, Howard Katzenstein, Marcio Malogolowkin, Logan Spector, Farzana Pashankar, Rebecka Meyers and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric blood & cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Journal of Cancer · 2021
    Article
  8. Review
  9. Fine Particulate Matter Air Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Children's Oncology Group: Organizational Structure, Membership, and Institutional Characteristics.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 1 country.

Carlos Rodriguez-GalindoDana-Farber/Children's Hospital Cancer Center, Harvard Medical School, Boston, MA 02115, USA. carlos_rodriguez-galindo@dfci.harvard.edu
Mark Krailo
Lindsay Frazier
Murali Chintagumpala
James Amatruda
Howard Katzenstein
Marcio Malogolowkin
Logan Spector
Farzana Pashankar
Rebecka Meyers
Gail Tomlinson
COG Rare Tumors Disease Committee
Arcadia · USBaylor College of Medicine · USChildren's Healthcare of Atlanta · USDana-Farber/Harvard Cancer Center · USHarvard University Press · USPrimary Children's Hospital · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas Southwestern Medical Center · USTwin Cities Orthopedics · USUniversity of Wisconsin–Milwaukee · USYale University · US

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI A. Heather Eliassen · 1985 to 2026
$330.6M
Generation and Rapid Mapping of Low-Penetrance Disease Alleles in ZebrafishR01CA135731 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI AMATRUDA, JAMES F · 2008 to 2012
$1.6M
NCI NIH HHS P30 CA006516NCI NIH HHS R01 CA135731
6 · The paper itself

Abstract

In the US, approximately 2,000 children are diagnosed with rare cancers each year, with 5-year survival ranging from <20% for children with advanced carcinomas to >95% for children with intraocular retinoblastoma or localized germ cell tumors. During the last years, 12 clinical studies have been successfully completed in children with retinoblastoma, liver tumors, germ cell tumors, and infrequent malignancies, including therapeutic, epidemiologic, and biologic studies. Current efforts are centered in the development of large international collaborations to consolidate evidence-based definitions and risk stratifications that will support international Phase 3 clinical trials in germ cell tumors, hepatoblastoma, and other rare cancers.

Indexed as

Clinical Trials as TopicChildHumansIncidenceNeoplasmsRare DiseasesResearch

Identifiers

PMID23255219
PMCPMC4304764
OpenAlexW2091279049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.