Evidence map›Paper›PMID 23255136›Full record

ReviewCell cycle (Georgetown, Tex.)2013

MicroRNA: a third dimension in autophagy.

Haiyan Zhai, Andrew Fesler, Jingfang Ju

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Mechanisms of DNA Damage Response in Mammalian Oocytes.Advances in anatomy, embryology, and cell biology · 2024
    Review
  3. Article
  4. Polyamines from myeloid-derived suppressor cells promote Th17 polarization and disease progression.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  5. Article
  6. miR-151 Affects Low-Temperature Tolerance ofFrontiers in cell and developmental biology · 2021
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Role of apoptosis and autophagy in tuberculosis.American journal of physiology. Lung cellular and molecular physiology · 2017
    Review
  17. Article
  18. microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Haiyan ZhaiTranslational Research Laboratory, Department of Pathology, Stony Brook University, Stony Brook, NY, USA.
Andrew Fesler
Jingfang Ju
Stony Brook University · USStony Brook Medicine · US

Funding

Molecular Mechanism of miR-140 in Colon CancerR01CA155019 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI JU, JINGFANG · 2011 to 2014
$1.5M
Identification of post-transcriptionally regulated targets by TrIP-Chip/SeqR33CA147966 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI JU, JINGFANG · 2011 to 2013
$674k
NCI NIH HHS R01 CA155019NCI NIH HHS R01CA155019NCI NIH HHS R33 CA147966NCI NIH HHS R33CA147966
6 · The paper itself

Abstract

Autophagy is a catabolic process that allows cellular macromolecules to be broken down and recycled into metabolic precursors. It is a highly conserved, critical process, allowing cells to gain survival advantages under various stress situations due to growth and environmental changes. In the past few years, mounting evidence indicates that the post-transcriptional and translational controls mediated by non-coding miRNAs contribute significantly to autophagy in cancer. Such acute modulation of protein synthesis mediated by miRNAs provides cells with advantages in response to starvation, genotoxic stress and hypoxia. In this review, we highlight some of the important discoveries and molecular insights of miRNAs in regulating autophagy based on various cancer models.

Indexed as

AutophagyCell DeathCell ProliferationDNA DamageGene Expression RegulationHumansHypoxiaMicroRNAsRNA, MessengerTumor Suppressor Protein p53MicroRNAsRNA, MessengerTumor Suppressor Protein p53autophagycancermicroRNA

Identifiers

PMID23255136
PMCPMC3575453
OpenAlexW1986742027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.