Evidence map›Paper›PMID 23254230›Full record

Trial reportAddictive behaviors2013

Predictors of cessation in African American light smokers enrolled in a bupropion clinical trial.

Babalola Faseru, Nicole L Nollen, Matthew S Mayo, Ron Krebill, Won S Choi, Neal L Benowitz, Rachel F Tyndale, Kolawole S Okuyemi, Jasjit S Ahluwalia, Lisa Sanderson Cox

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 8 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 8 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Interventions for preventing weight gain after smoking cessation.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Smoking cessation for improving mental health.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  5. Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Pooled it
  6. Pooled it
  7. A scoping review and meta-analysis of psychosocial and pharmacological treatments for cannabis and tobacco use among African Americans.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Pooled it
  8. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2014
    Pooled it
  9. Characteristics of Black Adults Who Never Achieved 24-Hours of Abstinence in a Smoking Cessation Trial: Implications for Improving Treatment Response.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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  17. A Method for Amending Loose Smokeless Tobacco With Menthol for Administration in Clinical Studies.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  18. Article
  19. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Babalola FaseruDepartment of Preventive Medicine and Public Health, University of Kansas School of Medicine, Kansas City, KS 66160, USA. bfaseru@kumc.edu
Nicole L Nollen
Matthew S Mayo
Ron Krebill
Won S Choi
Neal L Benowitz
Rachel F Tyndale
Kolawole S Okuyemi
Jasjit S Ahluwalia
Lisa Sanderson Cox
University of Kansas · USUniversity of Minnesota · USUniversity of California, San Francisco · USUniversity of Toronto · CA

Funding

Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON, JONES, REESE T. · 1999 to 2024
$17.1M
Project 2P20MD004805 · NIMHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI DALEY, CHRISTINE MAKOSKY, GREINER, K ALLEN · 2010 to 2014
$7.6M
The Center for Health Disparities Research, Engagement, and Training (CeHDRET)P60MD003422 · NIMHD · UNIVERSITY OF MINNESOTA · PI EVERSON-ROSE, SUSAN A. · 2009 to 2013
$6.1M
Helping African American Light Smokers QuitR01CA091912 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI COX, LISA SANDERSON · 2001 to 2010
$5.6M
Training ProgramU54CA154253 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI GREINER, K ALLEN · 2010 to 2015
$4.6M
Increasing Post-discharge Follow Up among Hospitalized SmokersU01HL105232 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI RICHTER, KIMBER P · 2010 to 2013
$2.9M
NCI NIH HHS R01 CA091912NCI NIH HHS R01CA091912NCI NIH HHS R01CA091912-09S1NCI NIH HHS U54 CA154253NHLBI NIH HHS U01 HL105232NIDA NIH HHS P30 DA012393NIDA NIH HHS P30DA12393NIMHD NIH HHS 1P60MD003422NIMHD NIH HHS P20 MD004805NIMHD NIH HHS P60 MD003422PHS HHS 5 D34 HP16041-03-0
6 · The paper itself

Abstract

backgroundThis is the first study to examine predictors of successful cessation in African American (AA) light smokers treated within a placebo-controlled trial of bupropion.

methodsWe analyzed data from a randomized, double-blind, placebo-controlled trial of bupropion and health education for 540 African American light smokers. African American light smokers (≤10 cigarettes per day, cpd) were randomly assigned to receive 150mg bid bupropion SR (n=270) or placebo (n=270) for 7weeks. All participants received health education counseling at weeks 0, 1, 3, 5 and 7. Using chi-square tests, two sample t-tests, and multiple logistic regression analyses, we examined baseline psychosocial and smoking characteristics as predictors of cotinine-verified 7-day point prevalence smoking abstinence among study participants at the end treatment (Week 7) and at the end of follow-up (Week 26).

resultsParticipants who received bupropion were significantly more likely to quit smoking compared to those who received placebo (OR=2.72, 95% CI=1.60-4.62, P=0.0002). Greater study session attendance (OR=2.47, 95% CI=1.76-3.46, P=0.0001), and smoking non-menthol cigarettes increased the likelihood of quitting (OR=1.84, 95% CI=1.01-3.36, P=0.05); while longer years of smoking (OR=0.98, 95% CI=0.96-1.00, P=0.05) and higher baseline cotinine (OR=0.97, 95% CI=0.95-0.99, P=0.002) significantly reduced the odds of quitting at Week 7. Conversely, at the end of follow-up (Week 26), treatment with bupropion vs. placebo (OR=1.14, 95% CI=0.65-2.02, P=0.64) was not significantly associated with quitting and type of cigarette smoked (menthol vs. non-menthol) did not appear in the final logistic regression model. Greater study session attendance (OR=1.96, 95% CI=1.44-2.66, P=0.0001); BMI (OR=1.03, 95% CI=1.00-1.07, P=0.04); and weight efficacy (OR=1.03, 95% CI=1.01-1.05, P=0.01) increased the likelihood of quitting at Week 26. Similar to our findings at Week 7, longer years of smoking (OR=0.96, 95% CI=0.94-0.99, P=0.01) and higher baseline cotinine (OR=0.97, 95% CI=0.95-0.99, P=0.02) significantly reduced the odds of quitting at Week 26.

conclusionsBaseline cotinine levels, number of years smoked and study session attendance are associated with both short- and long-term smoking cessation, while bupropion and the type of cigarette smoked were associated with quitting on short term only.

Indexed as

Smoking PreventionAdolescentAdultAgedBlack or African AmericanBupropionCombined Modality TherapyCounselingDopamine Uptake InhibitorsDouble-Blind MethodFemaleHealth EducationHumansMaleMiddle AgedSmoking CessationBupropionDopamine Uptake Inhibitors

Identifiers

PMID23254230
PMCPMC3558614
OpenAlexW1994473494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.