Evidence map›Paper›PMID 23254228›Full record

ArticleAddictive behaviors2013

Prescription opioid use among addictions treatment patients: nonmedical use for pain relief vs. other forms of nonmedical use.

Amy S B Bohnert, Anna Eisenberg, Lauren Whiteside, Amanda Price, Sean Esteban McCabe, Mark A Ilgen

Abstract read
In one paragraph

Article in Addictive behaviors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amy S B BohnertVA National Serious Mental Illness Treatment Resource and Evaluation Center and VA Health Services Research and Development, North Campus Research Complex, 2800 Plymouth Road, Building 14, Ann Arbor, MI 48109, USA. mybohne@med.umich.edu
Anna Eisenberg
Lauren Whiteside
Amanda Price
Sean Esteban McCabe
Mark A Ilgen

Funding

Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
A Prospective Study of the Nonmedical use of Prescription Medications by AdolesceR01DA024678 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYD, CAROL J · 2009 to 2013
$3.0M
Psychosocial pain management during addictions treatment to improve outcomesR01DA029587 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ILGEN, MARK A. · 2011 to 2015
$2.4M
Developing an intervention to address suicide risk during substance use disorderR21DA026925 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ILGEN, MARK A. · 2009 to 2010
$425k
HSRD VA CDA 09-204NIDA NIH HHS R01 DA024678NIDA NIH HHS R01DA024678NIDA NIH HHS R01 DA029587NIDA NIH HHS R01 DA031160NIDA NIH HHS R01DA031160NIDA NIH HHS R21 DA026925NIDA NIH HHS R21DA026925
6 · The paper itself

Abstract

backgroundDifferences between those who engage in nonmedical prescription opioid use for reasons other than pain relief and those who engage in nonmedical use for reasons related to pain only are not well understood.

methodsAdults in a residential treatment program participated in a cross-sectional self-report survey. Participants reported whether they used opioids for reasons other than pain relief (e.g., help sleep, improve mood, or relieve stress). Within those with past-month nonmedical opioid use (n=238), logistic regression tested differences between those who reported use for reasons other than pain relief and those who did not.

resultsNonmedical use of opioids for reasons other than pain relief was more common (66%) than nonmedical use for pain relief only (34%), and those who used for reasons other than pain relief were more likely to report heavy use (43% vs. 11%). Nonmedical use for reasons other than pain relief was associated with having a prior overdose (odds ratio [OR]=2.54, 95% CI: 1.36-4.74) and use of heroin (OR=4.08, 95% CI: 1.89-8.79), barbiturates (OR=6.44, 95% CI: 1.47, 28.11), and other sedatives (OR=5.80, 95% CI: 2.61, 12.87). Individuals who reported nonmedical use for reasons other than pain relief had greater depressive symptoms (13.1 vs. 10.5) and greater pain medication expectancies across all three domains (pleasure/social enhancement, pain reduction, negative experience reduction).

conclusionsAmong patients in addictions treatment, individuals who report nonmedical use of prescription opioids for reasons other than pain relief represent an important clinical sub-group with greater substance use severity and poorer mental health functioning.

Indexed as

Prescription Drug MisuseAdultAnalgesics, OpioidCross-Sectional StudiesFemaleHumansMaleOff-Label UsePainPain MeasurementPrescription DrugsResidential TreatmentSubstance-Related DisordersAnalgesics, OpioidPrescription Drugs

Identifiers

PMID23254228
PMCPMC4049343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.