Evidence map›Paper›PMID 23253220›Full record

ReviewExpert review of anticancer therapy2012

Emerging personalized approaches for the management of advanced urothelial carcinoma.

Che-Kai Tsao, Benjamin A Gartrell, William K Oh, Matthew D Galsky

Abstract readReview
In one paragraph

Review in Expert review of anticancer therapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Biomarkers for bladder cancer management: present and future.American journal of clinical and experimental urology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Che-Kai TsaoDivision of Hematology and Medical Oncology, Tisch Cancer Institute, Mount Sinai School of Medicine, NY, USA.
Benjamin A Gartrell
William K Oh
Matthew D Galsky

Funding

Novel Approach to Facilitate Decisions in Patients w/ Muscle Invasive Bladder CAR21CA176551 · NCI · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DIEFENBACH, MICHAEL A, GALSKY, MATTHEW · 2015 to 2016
$450k
NCI NIH HHS R21 CA176551
6 · The paper itself

Abstract

Urothelial carcinoma of the bladder comprises a spectrum of illnesses ranging from nonmuscle-invasive to muscle-invasive to advanced/metastatic disease. Each of these clinical states is characterized by a unique pathogenesis, prognosis and approach to treatment. However, given the heterogeneity of urothelial carcinoma, differences in biology and outcomes exist not only among these clinical states but also within each state. Personalized medicine, also commonly referred to as individualized or stratified medicine, offers the potential to optimize treatment for a given patient, based on the ability to accurately predict prognosis, response to treatment and tolerability of treatment. This review will discuss recent efforts, current challenges and future opportunities, for the personalized management of urothelial carcinoma.

Indexed as

Antineoplastic AgentsCarcinoma, Transitional CellCystectomyCystoscopyHumansPrecision MedicineUrinary Bladder NeoplasmsAntineoplastic Agents

Identifiers

PMID23253220
PMCPMC4744482

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.