Evidence map›Paper›PMID 23252992›Full record

ReviewTissue engineering. Part B, Reviews2013

Strategies and techniques to enhance the in situ endothelialization of small-diameter biodegradable polymeric vascular grafts.

Anthony J Melchiorri, Narutoshi Hibino, John P Fisher

Open access · greenAbstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 165 citations in OpenAlex.

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  5. Step-wise CAG@PLys@PDA-CuBioactive materials · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anthony J MelchiorriFischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, USA. amelchio@umd.edu
Narutoshi Hibino
John P Fisher
University of Maryland, College Park · US

Funding

Application of Tubular Perfusion System (TPS) Generated Prevascularized Bone TissR01AR061460 · NIAMS · UNIV OF MARYLAND, COLLEGE PARK · PI FISHER, JOHN P · 2011 to 2014
$1.3M
NIAMS NIH HHS R01 AR061460
6 · The paper itself

Abstract

Due to the lack of success in small-diameter (<6 mm) prosthetic vascular grafts, a variety of strategies have evolved utilizing a tissue-engineering approach. Much of this work has focused on enhancing the endothelialization of these grafts. A healthy, confluent endothelial layer provides dynamic control over homeo-stasis, influencing and preventing thrombosis and smooth muscle cell proliferation that can lead to intimal hyperplasia. Strategies to improve endothelialization of biodegradable polymeric grafts have encompassed both chemical and physical modifications to graft surfaces, many focusing on the recruitment of endothelial and endothelial progenitor cells. This review aims to provide a compilation of current and developing strategies that utilize in situ endothelialization to improve vascular graft outcomes, providing a context for the future directions of vascular tissue-engineering strategies that do not require preprocedural cell seeding.

Indexed as

Absorbable ImplantsBlood Vessel ProsthesisAnimalsEndothelium, VascularHumansTissue Engineering

Identifiers

PMID23252992
PMCPMC3690089
OpenAlexW1999528452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.