Evidence map›Paper›PMID 23252474›Full record

Trial reportEuropean journal of cancer care2013

Quality of life among advanced breast cancer patients with and without distant metastasis.

G Wyatt, A Sikorskii, D Tamkus, M You

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of cancer care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Chemotherapy interruptions in relation to symptom severity in advanced breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Quality of Life of Cancer Patients Treated with Chemotherapy.International journal of environmental research and public health · 2020
    Article
  8. Article
  9. Massage Therapy in Outpatient Cancer Care: A Metropolitan Area Analysis.Journal of evidence-based complementary & alternative medicine · 2017
    Article
  10. Article
  11. Article
  12. Article
  13. Spiritual well-being among outpatients with cancer receiving concurrent oncologic and palliative care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Article
  14. Article
  15. Article
  16. Quality of Life among Cancer Patients.Indian journal of palliative care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G WyattCollege of Nursing, Michigan State University, East Lansing, MI 48824-1317, USA. gwyatt@msu.edu
A Sikorskii
D Tamkus
M You

Funding

Reflexology: An Intervention for Advanced Breast CancerR01CA104883 · NCI · MICHIGAN STATE UNIVERSITY · PI WYATT, GWEN KARILYN · 2005 to 2009
$2.3M
NCI NIH HHS R01 CA104883NCI NIH HHS R01 CA104883-01A1
6 · The paper itself

Abstract

This study presents the results of a secondary analysis of data collected during a trial of reflexology that aimed to improve health-related quality of life (HRQOL) among women with advanced breast cancer in treatment. A comparison of HRQOL (functioning, symptoms, spirituality) of those with (n = 298) and without (n = 87) distant metastasis is presented. Following the intake interview, 385 women were randomised to reflexology, lay foot manipulation or conventional care control, and were interviewed again at weeks 5 and 11. Those with distant metastasis were older, had fewer comorbid conditions, and a smaller proportion were employed. Longitudinal analysis of HRQOL at intake, 5 and 11 weeks revealed that those with distant metastasis had lower functioning and more pain; however, no differences were found on fatigue, nausea, shortness of breath, sleep quality, anxiety, depressive symptoms or spirituality. Despite advanced disease, 56% of all women in this study were below the clinical screening cut-off for depressive symptoms. These findings may indicate that patients with advanced breast cancer have adapted emotionally and spiritually; however, the management of physical symptoms remains a priority.

Indexed as

Health StatusQuality of LifeAdaptation, PsychologicalAdultBreast NeoplasmsDepressionFemaleHumansMassageMiddle AgedYoung Adult

Identifiers

PMID23252474
PMCPMC3711236

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.