Evidence map›Paper›PMID 23251534›Full record

ArticlePloS one2012

Individual and population level effects of partner notification for Chlamydia trachomatis.

Christian L Althaus, Janneke C M Heijne, Sereina A Herzog, Adrian Roellin, Nicola Low

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Contact tracing - Old models and new challenges.Infectious Disease Modelling · 2021
    Article
  6. Article
  7. Does infection withSexually transmitted infections · 2019
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Adolescent patient preferences surrounding partner notification and treatment for sexually transmitted infections.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2015
    Article
  14. Defining research priorities for bacterial sexually transmitted infections in Canada.Canadian journal of public health = Revue canadienne de sante publique · 2014
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Christian L AlthausInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland. christian.althaus@alumni.ethz.ch
Janneke C M Heijne
Sereina A Herzog
Adrian Roellin
Nicola Low
University of Bern · CHInstitute of Social and Preventive Medicine · CH

Funding

Department of Health 07/42/02Department of Health HTA/07/42/02
6 · The paper itself

Abstract

Partner notification (PN or contact tracing) is an important aspect of treating bacterial sexually transmitted infections (STIs), such as Chlamydia trachomatis. It facilitates the identification of new infected cases that can be treated through individual case management. PN also acts indirectly by limiting onward transmission in the general population. However, the impact of PN, both at the level of individuals and the population, remains unclear. Since it is difficult to study the effects of PN empirically, mathematical and computational models are useful tools for investigating its potential as a public health intervention. To this end, we developed an individual-based modeling framework called Rstisim. It allows the implementation of different models of STI transmission with various levels of complexity and the reconstruction of the complete dynamic sexual partnership network over any time period. A key feature of this framework is that we can trace an individual's partnership history in detail and investigate the outcome of different PN strategies for C. trachomatis. For individual case management, the results suggest that notifying three or more partners from the preceding 18 months yields substantial numbers of new cases. In contrast, the successful treatment of current partners is most important for preventing re-infection of index cases and reducing further transmission of C. trachomatis at the population level. The findings of this study demonstrate the difference between individual and population level outcomes of public health interventions for STIs.

Indexed as

Chlamydia trachomatisAdolescentAdultChlamydia InfectionsComputer SimulationContact TracingFemaleHumansMaleMass ScreeningModels, BiologicalPopulation DynamicsPrevalenceSex CharacteristicsSexual PartnersTime Factors

Identifiers

PMID23251534
PMCPMC3520891
OpenAlexW2082722724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.