ArticleInternational journal of endocrinology2012
Association of lipids with oxidative stress biomarkers in subclinical hypothyroidism.
Article in International journal of endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 60 citations in OpenAlex.
- Oxidative DNA damage level and lipid peroxidation status in subclinical hypothyroid patients compared with euthyroid individuals.Journal of Taibah University Medical Sciences · 2026Article
- The interplay of serum cations, insulin resistance, and atherogenic indices in predicting depression in hypothyroid patients.Biotechnology reports (Amsterdam, Netherlands) · 2025Article
- Glutathione Peroxidase and Selenoprotein P Evaluation in Well-Being Assessment After Total Thyroidectomy.International journal of molecular sciences · 2025Article
- Magnitude, Pattern, and Associated Factors of Thyroid Dysfunction in Diabetic Patients at Debre Markos Referral Hospital in North-West Ethiopia: A Cross-Sectional Hospital-based Study.Ethiopian journal of health sciences · 2025Article
- Increased thyroid stimulating hormone (TSH) as a possible risk factor for atherosclerosis in subclinical hypothyroidism.Thyroid research · 2024Review
- Changes in biomarkers of redox status in serum and saliva of dogs with hypothyroidism.BMC veterinary research · 2023Article
- Menopausal Impact on the Association Between Thyroid Dysfunction and Lipid Profiles: A Cross-Sectional Study.Frontiers in endocrinology · 2022Article
- The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism.Antioxidants (Basel, Switzerland) · 2021Article
- Chinese Herbal Medicine Alleviates Thyroidectomy-Induced Cardiopulmonary Exercise Dysfunction in Rats.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- gp91International journal of endocrinology · 2020Article
- Effect of Bamboo Leaf Extract on Antioxidant Status and Cholesterol Metabolism in Broiler Chickens.Animals : an open access journal from MDPI · 2019Article
- Critical Period Regulation by Thyroid Hormones: Potential Mechanisms and Sex-Specific Aspects.Frontiers in molecular neuroscience · 2019Article
- Alteration in Prooxidant-antioxidant Balance Associated with Selenium Concentration in Patients with Congenital Hypothyroidism.Journal of medical biochemistry · 2018Article
- Levothyroxine Replacement Improves Oxidative Status in Primary Hypothyroidism.Frontiers in endocrinology · 2018Article
- Role of levothyroxine and vitamin E supplementation in the treatment of oxidative stress-induced injury and apoptosis of myocardial cells in hypothyroid rats.Journal of endocrinological investigation · 2017Article
- Epicardial fat thickness and oxidative stress parameters in patients with subclinical hypothyroidism.Archives of medical science : AMS · 2017Article
- Thyroid Hormones, Oxidative Stress, and Inflammation.Mediators of inflammation · 2016Review
- LDL in patients with subclinical hypothyroidism shows increased lipid peroxidation.Lipids in health and disease · 2015Article
- Association Between Thyroid Hormones, Lipids and Oxidative Stress Markers in Subclinical Hypothyroidism.Journal of medical biochemistry · 2015Article
- The relationships between thyroid hormones and thyroid-stimulating hormone with lipid profile in euthyroid men.International journal of medical sciences · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective. The aim of the present study was to evaluate the oxidative stress biomarkers in patients with subclinical hypothyroidism (n = 20) and health controls (n = 20). Subjects and Methods. Total cholesterol (TC), triglycerides (TGs), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), thiobarbituric acid reactive substances (TBARSs), catalase (CAT), superoxide dismutase (SOD), and arylesterase (ARE) were analyzed. Results. TC, LDL-C, TBARS, and CAT were higher in subclinical hypothyroidism patients, whereas SOD did not change. Arylesterase activity was significantly lower in the SH group, compared with the control group. Correlation analyses revealed the association of lipids (TC and LDL-C) with both oxidative stress biomarkers and thyrotropin (TSH). Thyroid hormones were correlated only with triglyceride levels. In addition, TSH was significantly correlated with TBARS, CAT, and SOD. However, no significant correlations were observed after controlling TC levels. Conclusions. We found that SH patients are under increased oxidative stress manifested by reduced ARE activity and elevated lipoperoxidation and CAT activity. Secondary hypercholesterolemia to thyroid dysfunction and not hypothyroidism per se appears to be associated with oxidative stress in subclinical hypothyroidism.
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Registered trials
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