Trial reportTheScientificWorldJournal2012
Allograft cellular bone matrix in extreme lateral interbody fusion: preliminary radiographic and clinical outcomes.
Trial report in TheScientificWorldJournal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- MIS lateral spine surgery: a systematic literature review of complications, outcomes, and economics.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2015Pooled it
- A study on the effect of platelet-rich plasma (PRP) to promote bone fusion in lateral interbody fusion of the lumbar spine using artificial bone.Journal of orthopaedic surgery and research · 2024Trial
- Twenty-four-month interim results from a prospective, single-arm clinical trial evaluating the performance and safety of cellular bone allograft in patients undergoing lumbar spinal fusion.BMC musculoskeletal disorders · 2023Trial
- 12-Month clinical and radiographic outcomes of ViBone viable bone matrix in patients undergoing cervical and lumbar spinal fusion surgery.Journal of orthopaedic surgery and research · 2023Trial
- Do Cellular Allografts Improve Spinal Fusion Enough to Justify Their Cost and Potential Risk? A Systematic Review of Efficacy, Safety, and Cost.Neurosurgery practice · 2026Review
- Clinical and radiographic outcomes of three-level anterior cervical discectomy and fusion using allograft cellular bone matrix.Journal of spine surgery (Hong Kong) · 2026Article
- Article
- High Lumbar Spinal Fusion Rates Using Cellular Bone Allograft Irrespective of Surgical Approach.International journal of spine surgery · 2024Article
- Cellular Bone Matrix in Spine Surgery - Are They Worth the Risk: A Systematic Review.Global spine journal · 2024Review
- Prone Transpsoas Lateral Interbody Fusion (PTP LIF) with Anterior Docking: Preliminary functional and radiographic outcomes.North American Spine Society journal · 2023Article
- Article
- Twelve-Month Results from a Prospective Clinical Study Evaluating the Efficacy and Safety of Cellular Bone Allograft in Subjects Undergoing Lumbar Spinal Fusion.Neurology international · 2022Article
- Is Platelet-Rich Plasma Effective in Enhancing Spinal Fusion? Systematic Overview of Overlapping Meta-Analyses.Global spine journal · 2022Article
- Lateral lumbar interbody fusion using a cellular allogeneic bone matrix in the treatment of symptomatic degenerative lumbar disc disease and lumbar spinal instability.Journal of spine surgery (Hong Kong) · 2021Article
- Commercial Bone Grafts Claimed as an Alternative to Autografts: Current Trends for Clinical Applications in Orthopaedics.Materials (Basel, Switzerland) · 2021Review
- Short-segment minimally disruptive anterior column release for focal sagittal deformity correction of the thoracolumbar spine.North American Spine Society journal · 2021Article
- Allografts and Spinal Fusion.International journal of spine surgery · 2021Article
- Stem Cells and Spinal Fusion.International journal of spine surgery · 2021Article
- The usefulness and safety of the simultaneous parallel anterior and posterior combined lumbar spine surgery using intraoperative 3D fluoroscopy-based navigation (SPAPS).North American Spine Society journal · 2021Article
- Intraoperative image guidance for lateral position surgery.Annals of translational medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionExtreme lateral interbody fusion (XLIF) is a minimally disruptive alternative for anterior lumbar interbody fusion. Recently, synthetic and allograft materials have been increasingly used to eliminate donor-site pain and complications secondary to autogenous bone graft harvesting. The clinical use of allograft cellular bone graft has potential advantages over autograft by eliminating the need to harvest autograft while mimicking autograft's biologic function. The objective of this study was to examine 12-month radiographic and clinical outcomes in patients who underwent XLIF with Osteocel Plus, one such allograft cellular bone matrix.
methodsForty (40) patients were treated at 61 levels with XLIF and Osteocel Plus and included in the analysis.
resultsNo complications were observed. From preoperative to 12-month postoperative followup, ODI improved 41%, LBP improved 55%, leg pain improved 43.3%, and QOL (SF-36) improved 56%. At 12 months, 92% reported being "very" or "somewhat" satisfied with their outcome and 86% being either "very" or "somewhat likely" to choose to undergo the procedure again. Complete fusion was observed in 90.2% (55/61) of XLIF levels.
conclusionsComplete interbody fusion with Osteocel Plus was shown in 90.2% of XLIF levels, with the remaining 9.8% being partially consolidated and progressing towards fusion at 12 months.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.