Evidence map›Paper›PMID 23250817›Full record

ReviewCurrent psychiatry reports2013

Gene-environment studies and borderline personality disorder: a review.

Ryan W Carpenter, Rachel L Tomko, Timothy J Trull, Dorret I Boomsma

Abstract readReview
In one paragraph

Review in Current psychiatry reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Network analysis of the genetic relationships between twenty psychiatric and substance use disorders.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  2. Review
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  11. Review
  12. Article
  13. Observational
  14. Article
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  16. Review
  17. Article
  18. Article
  19. Complex PTSD, affect dysregulation, and borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan W CarpenterDepartment of Psychological Sciences, University of Missouri, 210 McAlester Hall, Columbia, MO, USA.
Rachel L Tomko
Timothy J Trull
Dorret I Boomsma

Funding

Psychology of Alcohol Use and Dependence TrainingT32AA013526 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI DENIS M MCCARTHY, KENNETH JAMES SHER · 2002 to 2026
$9.0M
NIAAA NIH HHS T32 AA013526
6 · The paper itself

Abstract

We review recent gene-environment studies relevant to borderline personality disorder, including those focusing on impulsivity, emotion sensitivity, suicidal behavior, aggression and anger, and the borderline personality phenotype itself. Almost all the studies reviewed suffered from a number of methodological and statistical problems, limiting the conclusions that currently can be drawn. The best evidence to date supports a gene-environment correlation (rGE) model for borderline personality traits and a range of adverse life events, indicating that those at risk for BPD are also at increased risk for exposure to environments that may trigger BPD. We provide suggestions regarding future research on GxE interaction and rGE effects in borderline personality.

Indexed as

Gene-Environment InteractionAggressionBorderline Personality DisorderEmotionsGenetic Predisposition to DiseaseHumansImpulsive BehaviorPhenotypeRisk FactorsSuicidal Ideation

Identifiers

PMID23250817
PMCPMC3973430

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.