Evidence map›Paper›PMID 23249878›Full record

Trial reportEuropean journal of clinical nutrition2013

Does peritoneal dialysate affect body composition assessments using multi-frequency bioimpedance in peritoneal dialysis patients?

A Davenport

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Bioelectrical Impedance in Pediatric Dialysis: Clinical Applications, Limitations, and Opportunities.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Serum CA125 a potential marker of volume status for peritoneal dialysis patients?The International journal of artificial organs · 2021
    Article
  10. Review
  11. Review
  12. Article
  13. Muscle mass assessment in renal disease: the role of imaging techniques.Quantitative imaging in medicine and surgery · 2020
    Review
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

A DavenportUCL Centre for Nephrology, Royal Free Hospital, University College London Medical School, London, UK. andrewdavenport@nhs.net

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMulti-frequency bioelectrical impedance analysis (MFBIA) is increasingly being used to assess peritoneal dialysis patients. Protein energy wasting (PEW) is a recognised complication of peritoneal dialysis. Although MFBIA can be used to assess body composition, measurements can be affected by fluid overload, and we wished to determine whether the presence of peritoneal dialysate in the peritoneal cavity equally could affect MFBIA-derived body composition assessments. SUBJECTS/

methodsFifty consecutive adult patients had MFBIA made with 2l 22.7 g/l dextrose dialysate instilled into the peritoneal cavity and then after draining out.

resultsWhen full, extracellular water (ECW) and the ratio of ECW to total body water (TBW) were greater compared with when empty: 13.9 ± 3.0l versus 13.4 ± 3.0, and 0.393 ± 0.01 versus 0.391 ± 0.01, P<0.001, respectively. Segmental ECW/TBW was only different for the trunk, 0.395 ± 0.01 full versus 0.392 ± 0.01 empty, P<0.0001. Body composition changed with a fall in skeletal muscle mass from 26.1 ± 6.3 to 25.2 ± 6.1 kg, P<0.001, and a smaller reduction in body fat from 19.3 ± 8.4 to 19.1 ± 8.0 kg, P=0.0104.

conclusionMFBIA measurements made in peritoneal dialysis patients with peritoneal dialysate instilled can overestimate body composition, including muscle mass, and as such potentially delay the recognition of PEW. Thus, for more accurate MFBIA in peritoneal dialysis patients, the dialysate should be drained out.

Indexed as

Body CompositionBody WaterDialysis SolutionsElectric ImpedanceAdipose TissueAdultAgedExtracellular MatrixFemaleGlucoseHumansMaleMiddle AgedMuscle, SkeletalPeritoneal DialysisProtein-Energy MalnutritionDialysis SolutionsGlucose

Identifiers

PMID23249878

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.