ArticleThe American journal of tropical medicine and hygiene2013
Looking for Tropheryma whipplei source and reservoir in rural Senegal.
Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- A compilation of ticks and tick-borne pathogen distributions in seven countries within North and West Africa from 1901 to 2022: a systematic literature review.Parasites & vectors · 2025Pooled it
- Rare but Critical: SevereClinical case reports · 2026Article
- A case of pulmonary nodular lesion caused by Tropheryma whipplei infection: a case report and literature review.BMC pulmonary medicine · 2025Review
- Whipple Disease Presenting as Isolated Transverse Myelitis with Permanent Neurological Damage in a Patient with Systemic Lupus Erythematosus: A Case Report of a Difficult Diagnosis with a Literature Review.Infectious disease reports · 2024Article
- Design of a Multi-Epitope Vaccine againstVaccines · 2022Article
- Clinical manifestations of Whipple's disease mimicking rheumatic disorders.Reumatologia · 2021Review
- Whipple's Disease: A Well-Done Outcome to a Rare Disease.Digestive diseases and sciences · 2019Article
- Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease.Infection and immunity · 2017Article
- Clinical Manifestations, Treatment, and Diagnosis of Tropheryma whipplei Infections.Clinical microbiology reviews · 2017Review
- FluorescenceFrontiers in medicine · 2017Article
- Implementation of Syndromic Surveillance Systems in Two Rural Villages in Senegal.PLoS neglected tropical diseases · 2016Article
- Tropheryma whipplei as a Cause of Epidemic Fever, Senegal, 2010-2012.Emerging infectious diseases · 2016Article
- High prevalence of Tropheryma whipplei in Lao kindergarten children.PLoS neglected tropical diseases · 2015Article
- Methods for the discovery of emerging pathogens.Microbial pathogenesis · 2014Review
- Gorilla gorilla gorilla gut: a potential reservoir of pathogenic bacteria as revealed using culturomics and molecular tools.Scientific reports · 2014Article
- Molecular identification of pathogenic bacteria in eschars from acute febrile patients, Senegal.The American journal of tropical medicine and hygiene · 2014Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tropheryma whipplei, the bacterium linked to Whipple's disease, is involved in acute infections and asymptomatic carriage. In rural Senegal, the prevalence of T. whipplei is generally high but is not homogeneous throughout households in the same village. We studied environmental samples collected in two Senegalese villages and conducted the survey to investigate the difference between households. Overall, the comparison between five households with very high T. whipplei prevalence and three households without any registered cases showed that the only difference was the presence of toilets in the latter (1/5 versus 3/3; P = 0.01423). Among the 1,002 environmental specimens (including domestic and synanthropic animals and dust sampled in households) tested for T. whipplei DNA, only four specimens were slightly positive. Humans are currently the predominant identified reservoir and source of T. whipplei in these populations. Limited access to toilets and exposure to human feces facilitate the fecal-oral transmission of T. whipplei.
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Registered trials
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