ArticleThe open orthopaedics journal2012
Current concepts of prophylactic antibiotics in trauma: a review.
Article in The open orthopaedics journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The 2023 WSES guidelines on the management of trauma in elderly and frail patients.World journal of emergency surgery : WJES · 2024Guideline
- Antibiotic prophylaxis in injury: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.Trauma surgery & acute care open · 2024Article
- Current status of initial antibiotic therapy and analysis of infections in patients with solitary abdominal trauma: a multicenter trial in Korea.Annals of surgical treatment and research · 2021Article
- Antibiotic use among surgical inpatients at a tertiary health facility: a case for a standardized protocol for presumptive antimicrobial therapy in the developing world.Infection prevention in practice · 2020Article
- Timing of antimicrobial initiation and reduced infection risk in open limb fractures: a cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- New automated analysis to monitor neutrophil function point-of-care in the intensive care unit after trauma.Intensive care medicine experimental · 2020Article
- Risk Factors of Bacteremia following Multiple Traumas.Emergency medicine international · 2020Article
- Antimicrobial Prophylaxis with Combat-Related Open Soft-Tissue Injuries.Military medicine · 2018Article
- Observational
- Early infectious outcomes after addition of fluoroquinolone or aminoglycoside to posttrauma antibiotic prophylaxis in combat-related open fracture injuries.The journal of trauma and acute care surgery · 2017Article
- Prevalence of inappropriate antibiotic prescriptions after the great east Japan earthquake, 2011.Medicine · 2017Article
- Variation in Postinjury Antibiotic Prophylaxis Patterns Over Five Years in a Combat Zone.Military medicine · 2017Article
- The Second Look after Fights: Why Wounds Might Not Only Be Superficial.Case reports in emergency medicine · 2016Article
- Predebridement wound culture in open fractures does not predict postoperative wound infection: A pilot study.Journal of natural science, biology, and medicine · 2015Article
- Controversies in the management of open fractures.The open orthopaedics journal · 2014Article
- Mammalian bite injuries to the hand and their management.The open orthopaedics journal · 2014Article
- Cefazolin and an aminoglycoside compared with cefazolin alone for the antimicrobial prophylaxis of type III open orthopedic fractures.International journal of critical illness and injury scienceArticle
- What is the right gentamicin dose for multiple trauma patients? A Monte Carlo simulation exploration study.International journal of critical illness and injury scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic injuries cause 5.8 million deaths per year globally. Before the advent of antibiotics, sepsis was considered almost inevitable after injury. Today infection continues to be a common complication after traumatic injury and is associated with increases in morbidity and mortality and longer hospital stays. Research into the prevention of post-traumatic infection has predominantly focused on thoracic and abdominal injuries. In addition, because research on sepsis following musculoskeletal injuries has predominantly been on open fractures. There is a paucity of research into the prevention of soft tissue infections following traumatic injuries. This review analyses the evidence for the role of prophylactic antibiotics in the management of soft tissue injuries. Emphasis is placed on assessing the strength of the presented evidence according to the Oxford Level of Evidence scale.
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Registered trials
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