Evidence map›Paper›PMID 23248712›Full record

ArticleDeutsches Arzteblatt international2012

Tourette syndrome and other tic disorders in childhood, adolescence and adulthood.

Andrea G Ludolph, Veit Roessner, Alexander Münchau, Kirsten Müller-Vahl

Abstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Knowledge and Awareness of Tourette's Syndrome among Teachers in Eastern Region, Saudi Arabia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Deep brain stimulation for Tourette's syndrome.The Cochrane database of systematic reviews · 2024
    Article
  10. Article
  11. Article
  12. Therapeutic use of medical Cannabis in neurological diseases: a clinical update.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Course of tic disorders over the lifespan.Current developmental disorders reports · 2021
    Article
  18. Article
  19. [Bertolt Brecht. Did he really have rheumatic fever?]Zeitschrift fur Rheumatologie · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Andrea G LudolphDepartment of Child- and Adolescent Psychiatry and Psychotherapy, Ulm University Hospital, Ulm, Germany. andrea.ludolph@uni-ulm.de
Veit Roessner
Alexander Münchau
Kirsten Müller-Vahl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTourette syndrome is a combined motor and vocal tic disorder that begins in childhood and takes a chronic course. It arises in about 1% of all children, with highly varying severity. Transient and usually mild tics are seen in as many as 15% of all children in elementary school. The diagnosis is often delayed by several years.

methodsWe selectively reviewed the pertinent literature, including the guidelines of the European Society for the Study of Tourette Syndrome for the diagnosis and treatment of tic disorders.

resultsTic disorders usually take a benign course, with spontaneous improvement in adolescence in about 90% of patients. Psychoeducation is the basis of treatment in each case and almost always brings marked emotional relief. Specific treatment is needed only for more severe tics and those that cause evident psychosocial impairment. 80-90% of patients with Tourette syndrome have comorbidities (attention deficit-hyperactivity disorder, obsessive-compulsive disorder, depression, anxiety, emotional dysregulation, autoaggression), which often impair their quality of life more than the tics do and therefore become the main target of treatment. There is little evidence for the efficacy of treatment for tics. Small-scale controlled studies with a brief follow-up period have been carried out for some neuroleptic drugs. Behavior therapy should be tried before drug treatment. A further option for very severely affected adults is deep brain stimulation.

conclusionBecause of the low level of the available evidence, no definitive recommendations can be made for the treatment of tics.

Indexed as

AdolescentBehavior TherapyChildChild, PreschoolEuropeFemaleHumansMalePatient Education as TopicPsychotherapyTicsTourette SyndromeYoung Adult

Identifiers

PMID23248712
PMCPMC3523260

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.