ArticleIsrael journal of chemistry2012
Photodynamic Therapy for Cancer and for Infections: What Is the Difference?
Article in Israel journal of chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 98 citations in OpenAlex.
- The Role of MALDI-TOF Mass Spectrometry in Photodynamic Therapy: From Photosensitizer Design to Clinical Applications.Current issues in molecular biology · 2025Review
- Versatile Porphyrin Arrangements for Photodynamic Therapy-A Review.Nanomaterials (Basel, Switzerland) · 2024Review
- Effect of Hyaluronic Acid on the Activity of Methylene Blue in Photogeneration ofMolecules (Basel, Switzerland) · 2024Article
- Dendrimers: Advancements and Potential Applications in Cancer Diagnosis and Treatment-An Overview.Pharmaceutics · 2023Review
- The effectiveness of antimicrobial photodynamic therapy with prodigiosin against reference strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.Lasers in medical science · 2022Article
- Selenophene-Modified Boron Dipyrromethene-Based Photosensitizers Exhibit Photodynamic Inhibition on a Broad Range of Bacteria.ACS omega · 2022Article
- Gallium Mesoporphyrin IX-Mediated Photodestruction: A Pharmacological Trojan Horse Strategy To Eliminate Multidrug-ResistantMolecular pharmaceutics · 2022Article
- In Vivo Potentiation of Antimicrobial Photodynamic Therapy in a Mouse Model of Fungal Infection by Addition of Potassium Iodide.Methods in molecular biology (Clifton, N.J.) · 2022Article
- In Vitro Potentiation of Antimicrobial Photodynamic Inactivation by Addition of Potassium Iodide.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Nanoparticle Systems for Cancer Phototherapy: An Overview.Nanomaterials (Basel, Switzerland) · 2021Review
- Diamond Nanoparticles-Porphyrin mTHPP Conjugate as Photosensitizing Platform: Cytotoxicity and Antibacterial Activity.Nanomaterials (Basel, Switzerland) · 2021Article
- Current Limitations and Recent Progress in Nanomedicine for Clinically Available Photodynamic Therapy.Biomedicines · 2021Review
- Utility of Photodynamic Therapy in Dentistry: Current Concepts.Dentistry journal · 2020Review
- Autophagy Regulation and Photodynamic Therapy: Insights to Improve Outcomes of Cancer Treatment.Frontiers in oncology · 2020Review
- Photodynamic antimicrobial chemotherapy in mice with Pseudomonas aeruginosa-infected wounds.PloS one · 2020Article
- Genetically Encoded Photosensitizers as Light-Triggered Antimicrobial Agents.International journal of molecular sciences · 2019Article
- Tetracyclines: light-activated antibiotics?Future medicinal chemistry · 2019Review
- Can light-based approaches overcome antimicrobial resistance?Drug development research · 2019Review
- Encapsulation of Gold Nanorods with Porphyrins for the Potential Treatment of Cancer and Bacterial Diseases: A Critical Review.Bioinorganic chemistry and applications · 2019Review
- Comparison of thiocyanate and selenocyanate for potentiation of antimicrobial photodynamic therapy.Journal of biophotonics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Photodynamic therapy (PDT) was discovered over one hundred years ago when it was observed that certain dyes could kill microorganisms when exposed to light in the presence of oxygen. Since those early days, PDT has mainly been developed as a cancer therapy and as a way to destroy proliferating blood vessels. However, recently it has become apparent that PDT may also be used as an effective antimicrobial modality and a potential treatment for localized infections. This review discusses the similarities and differences between the application of PDT for the treatment of microbial infections and for cancer lesions. Type I and type II photodynamic processes are described, and the structure-function relationships of optimal anticancer and antimicrobial photosensitizers are outlined. The different targeting strategies, intracellular photosensitizer localization, and pharmacokinetic properties of photosensitizers required for these two different PDT applications are compared and contrasted. Finally, the ability of PDT to stimulate an adaptive or innate immune response against pathogens and tumors is also covered.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.