ArticleProceedings of the National Academy of Sciences of the United States of America2013
Chytrid fungus Batrachochytrium dendrobatidis has nonamphibian hosts and releases chemicals that cause pathology in the absence of infection.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 187 citations in OpenAlex.
- Are novel or locally adapted pathogens more devastating and why? Resolving opposing hypotheses.Ecology letters · 2024Pooled it
- Spillover dynamics and asynchronous temporal fluctuations in host density and competence drive fungal parasite persistence in multi-host, seasonal communities.The Journal of animal ecology · 2026Article
- From protection to amplification: Imperfect chytridiomycosis prophylaxis increases infections in wild amphibians.bioRxiv : the preprint server for biology · 2026Article
- Metagenomic profiling of bacterial and fungal microbiota and putative pathogens of southern greater gliders (Petauroides volans).Animal microbiome · 2026Article
- Field Survey of Freshwater Invertebrates Reveals That Several Groups Are Potential Carriers of the Fungal PathogenEcology and evolution · 2026Article
- Investigating the potential neurotoxic effects of cell-free factors by Batrachochytrium dendrobatidis on locomotion in Xenopus laevis.Biology open · 2026Article
- Exposure toPeerJ · 2025Article
- Double-edged effects of aquatic environmental biofilms onISME communications · 2025Article
- Centrifugation is an effective and inexpensive way to determine Batrachochytrium dendrobatidis quantity in water samples with low turbidity.Oecologia · 2024Article
- Article
- Drosophila melanogaster as a model arthropod carrier for the amphibian chytrid fungus Batrachochytrium dendrobatidis.PloS one · 2024Article
- Chytrid infections exhibit historical spread and contemporary seasonality in a declining stream-breeding frog.Royal Society open science · 2024Article
- AmphibianVirulence · 2023Article
- The role of Culex territans mosquitoes in the transmission of Batrachochytrium dendrobatidis to amphibian hosts.Parasites & vectors · 2023Article
- The global risk of infectious disease emergence from giant land snail invasion and pet trade.Parasites & vectors · 2023Review
- Pseudacris regilla metamorphs acquire resistance to Batrachochytrium dendrobatidis after exposure to the killed fungus.Diseases of aquatic organisms · 2023Article
- Selection of an anti-pathogen skin microbiome following prophylaxis treatment in an amphibian model system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Identification of a novel secreted metabolite cyclo(phenylalanyl-prolyl) from Batrachochytrium dendrobatidis and its effect on Galleria mellonella.BMC microbiology · 2022Article
- Biodiversity is decimated by the cascading effects of the amphibian-killing chytrid fungus.PLoS pathogens · 2022Article
- Exposure to Batrachochytrium dendrobatidis affects chemical defences in two anuran amphibians, Rana dalmatina and Bufo bufo.BMC ecology and evolution · 2021Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Batrachochytrium dendrobatidis, a pathogenic chytrid fungus implicated in worldwide amphibian declines, is considered an amphibian specialist. Identification of nonamphibian hosts could help explain the virulence, heterogeneous distribution, variable rates of spread, and persistence of B. dendrobatidis in freshwater ecosystems even after amphibian extirpations. Here, we test whether mosquitofish (Gambusia holbrooki) and crayfish (Procambarus spp. and Orconectes virilis), which are syntopic with many amphibian species, are possible hosts for B. dendrobatidis. Field surveys in Louisiana and Colorado revealed that zoosporangia occur within crayfish gastrointestinal tracts, that B. dendrobatidis prevalence in crayfish was up to 29%, and that crayfish presence in Colorado wetlands was a positive predictor of B. dendrobatidis infections in cooccurring amphibians. In experiments, crayfish, but not mosquitofish, became infected with B. dendrobatidis, maintained the infection for at least 12 wk, and transmitted B. dendrobatidis to amphibians. Exposure to water that previously held B. dendrobatidis also caused significant crayfish mortality and gill recession. These results indicate that there are nonamphibian hosts for B. dendrobatidis and suggest that B. dendrobatidis releases a chemical that can cause host pathology, even in the absence of infection. Managing these biological reservoirs for B. dendrobatidis and identifying this chemical might provide new hope for imperiled amphibians.
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