Evidence map›Paper›PMID 23248053›Full record

ArticleHealth care analysis : HCA : journal of health philosophy and policy2015

Beyond bench and bedside: disentangling the concept of translational research.

Anna Laura van der Laan, Marianne Boenink

Abstract read
In one paragraph

Article in Health care analysis : HCA : journal of health philosophy and policy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A systematic review of theories, models and frameworks used for youth engagement in health research.Health expectations : an international journal of public participation in health care and health policy · 2024
    Pooled it
  2. Pooled it
  3. A scoping review of computational models on human glucose cerebral metabolism.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  4. Review
  5. Degree Background and NIH K-to-R01 Transition Among Investigators Using Experimental Neuroscience to Advance Psychiatry.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
  6. Article
  7. When Did the Term "Translational Research" Emerge-and Why?Journal of Korean medical science · 2026
    Article
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  9. Article
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  12. Review
  13. Article
  14. Scope highlights ofAnnals of translational medicine · 2023
    Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anna Laura van der LaanDepartment of Philosophy, Faculty of Behavioural Sciences, University of Twente, P.O. Box 217, 7500 AD, Enschede, The Netherlands, a.l.vanderlaan@utwente.nl.
Marianne Boenink

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The label 'Translational Research' (TR) has become ever more popular in the biomedical domain in recent years. It is usually presented as an attempt to bridge a supposed gap between knowledge produced at the lab bench and its use at the clinical bedside. This is claimed to help society harvest the benefits of its investments in scientific research. The rhetorical as well as moral force of the label TR obscure, however, that it is actually used in very different ways. In this paper, we analyse the scientific discourse on TR, with the aim to disentangle and critically evaluate the different meanings of the label. We start with a brief reconstruction of the history of the concept. Subsequently, we unravel how the label is actually used in a sample of scientific publications on TR and examine the presuppositions implied by different views of TR. We argue that it is useful to distinguish different views of TR on the basis of three dimensions, related to (1) the construction of the 'translational gap'; (2) the model of the translational process; and (3) the cause of the perceived translational gap. We conclude that the motive to make society benefit from its investments in biomedical science may be laudable, but that it is doubtful whether the dominant views of TR will contribute to this end.

Indexed as

Diffusion of InnovationEvidence-Based MedicineTranslational Research, BiomedicalHumans

Identifiers

PMID23248053
PMCPMC4293498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.