ArticleProtoplasma2013
Mitochondrial VDAC and hexokinase together modulate plant programmed cell death.
Article in Protoplasma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Identification and Characterization of VDAC Family in Maize.Plants (Basel, Switzerland) · 2023Article
- ROS accumulation-induced tapetal PCD timing changes leads to microspore abortion in cotton CMS lines.BMC plant biology · 2023Article
- Oxylipins and Reactive Carbonyls as Regulators of the Plant Redox and Reactive Oxygen Species Network under Stress.Antioxidants (Basel, Switzerland) · 2023Review
- Long noncoding RNAs: glycolysis regulators in gynaecologic cancers.Cancer cell international · 2023Review
- The boundary of life and death: changes in mitochondrial and cytosolic proteomes associated with programmed cell death ofFrontiers in plant science · 2023Article
- The mutual interaction of glycolytic enzymes and RNA in post-transcriptional regulation.RNA (New York, N.Y.) · 2022Review
- Overexpression of a Voltage-Dependent Anion-Selective Channel (VDAC) Protein-Encoding Gene,Genes · 2021Article
- Prunus Hexokinase 3 genes alter primary C-metabolism and promote drought and salt stress tolerance in Arabidopsis transgenic plants.Scientific reports · 2021Article
- Voltage-Dependent Anion-Selective Channels and Other Mitochondrial Membrane Proteins Form Diverse Complexes in Beetroots Subjected to Flood-Induced Programmed Cell Death.Frontiers in plant science · 2021Article
- Functional Characterization of VDACs in Grape and Its Putative Role in Response to Pathogen Stress.Frontiers in plant science · 2021Article
- Moonlighting Proteins: The Case of the Hexokinases.Frontiers in molecular biosciences · 2021Review
- VDACs: An Outlook on Biochemical Regulation and Function in Animal and Plant Systems.Frontiers in physiology · 2021Review
- Effects of Salicylic Acid on the Metabolism of Mitochondrial Reactive Oxygen Species in Plants.Biomolecules · 2020Review
- Salicylic acid-induced ROS production by mitochondrial electron transport chain depends on the activity of mitochondrial hexokinases in tomato (Solanum lycopersicum L.).Journal of plant research · 2019Article
- Article
- Grapevine VpPR10.1 functions in resistance to Plasmopara viticola through triggering a cell death-like defence response by interacting with VpVDAC3.Plant biotechnology journal · 2018Article
- Structure, Expression, and Functional Analysis of the Hexokinase Gene Family in Cassava.International journal of molecular sciences · 2017Article
- Dissecting the Metabolic Role of Mitochondria during Developmental Leaf Senescence.Plant physiology · 2016Article
- The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes.Biophysical journal · 2016Article
- Regulation of VDAC trafficking modulates cell death.Cell death discovery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The voltage-dependent anion channel (VDAC) and mitochondrially located hexokinase have been implicated both in pathways leading to cell death on the one hand, and immortalization in tumor formation on the other. While both proteins have also been implicated in death processes in plants, their interaction has not been explored. We have examined cell death following heterologous expression of a rice VDAC in the tobacco cell line BY2 and in leaves of tobacco plants and show that it is ameliorated by co-expression of hexokinase. Hexokinase also abrogates death induced by H2O2. We conclude that the ratio of expression of the two proteins and their interaction play a major role in modulating death pathways in plants.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.