Evidence map›Paper›PMID 23247327›Full record

ReviewOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2013

Impact of nutrition on muscle mass, strength, and performance in older adults.

A Mithal, J-P Bonjour, S Boonen, P Burckhardt, H Degens, G El Hajj Fuleihan, R Josse, P Lips, J Morales Torres, R Rizzoli and 5 more

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 144 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 6 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 6 syntheses or guidelines pooled it, 301 citations in OpenAlex.

  1. Pooled it
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  3. Prevalence of Sarcopenia in Africa: A Systematic Review.Clinical interventions in aging · 2023
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  10. Effect ofInternational journal of environmental research and public health · 2020
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84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 10 countries.

A MithalMedanta Medicity, Sector 38, Gurgaon, India. ambrishmithal@hotmail.com
J-P Bonjour
S Boonen
P Burckhardt
H Degens
G El Hajj Fuleihan
R Josse
P Lips
J Morales Torres
R Rizzoli
N Yoshimura
D A Wahl
C Cooper
B Dawson-Hughes
IOF CSA Nutrition Working Group
Manchester Metropolitan University · GBSt. Michael's Hospital · CATufts University · USUniversity Hospital of Geneva · CHAmsterdam UMC Location Vrije Universiteit Amsterdam · NLBone Health and Osteoporosis Foundation · USHirslanden Clinique Bois-Cerf · CHMedanta The Medicity · INMedanta The Medicity · INSouthampton General Hospital · GB

Funding

Medical Research Council MC_U147585824Medical Research Council MC_UP_A620_1014
6 · The paper itself

Abstract

Muscle strength plays an important role in determining risk for falls, which result in fractures and other injuries. While bone loss has long been recognized as an inevitable consequence of aging, sarcopenia-the gradual loss of skeletal muscle mass and strength that occurs with advancing age-has recently received increased attention. A review of the literature was undertaken to identify nutritional factors that contribute to loss of muscle mass. The role of protein, acid-base balance, vitamin D/calcium, and other minor nutrients like B vitamins was reviewed. Muscle wasting is a multifactorial process involving intrinsic and extrinsic alterations. A loss of fast twitch fibers, glycation of proteins, and insulin resistance may play an important role in the loss of muscle strength and development of sarcopenia. Protein intake plays an integral part in muscle health and an intake of 1.0-1.2 g/kg of body weight per day is probably optimal for older adults. There is a moderate [corrected] relationship between vitamin D status and muscle strength. Chronic ingestion of acid-producing diets appears to have a negative impact on muscle performance, and decreases in vitamin B12 and folic acid intake may also impair muscle function through their action on homocysteine. An adequate nutritional intake and an optimal dietary acid-base balance are important elements of any strategy to preserve muscle mass and strength during aging.

Indexed as

AgedAgingDietary ProteinsElder Nutritional Physiological PhenomenaHumansMalnutritionMuscle StrengthNutritional StatusSarcopeniaVitamin DDietary ProteinsVitamin D

Identifiers

PMID23247327
OpenAlexW2108272307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.