ArticleJournal of bone and mineral metabolism2013
Dissimilarity of femur aging in men and women from a Nationwide Survey in Korea (KNHANES IV).
Article in Journal of bone and mineral metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Low expression of SGCA promotes lung squamous cell carcinoma malignant progression.Scientific reports · 2025Article
- Serum uric acid/creatinine ratio and osteoporosis in the elderly: a NHANES study.Frontiers in medicine · 2025Article
- Article
- Acute kidney injury after hip fracture surgery in patients over 80 years of age.Archives of orthopaedic and trauma surgery · 2022Article
- The Characteristics of Women with Subsequent Distal Radius Fracture after Initial Distal Radius Fracture.Journal of bone metabolism · 2021Article
- Favorable effects of skeletal muscle on bone are distinguished according to gender and skeletal sites.Osteoporosis and sarcopenia · 2017Article
- Site-Specific Difference of Bone Geometry Indices in Hypoparathyroid Patients.Endocrinology and metabolism (Seoul, Korea) · 2017Article
- Lower Serum Creatinine Is Associated with Low Bone Mineral Density in Subjects without Overt Nephropathy.PloS one · 2015Article
- Familial interactions and physical, lifestyle, and dietary factors to affect bone mineral density of children in the KNHANES 2009-2010.Journal of bone and mineral metabolism · 2014Article
- Gender-specific pleiotropic bone-muscle relationship in the elderly from a nationwide survey (KNHANES IV).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- Association between depressive symptoms and bone stiffness index in young adults: the Kangwha study.PloS one · 2013Article
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In light of the differences in hip fracture rates between men and women of different ages, age-related changes in bone structure that lead to bone fragility might differ depending on both age and gender. To investigate age-related bone loss and geometric deterioration of the femur, hip scans of 1,504 men and 2,076 women aged 19-92 years acquired during the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV) using dual-energy X-ray absorptiometry (DXA) were analyzed with a structural analysis program. Cross-sectional area and cortical thickness with bone mineral density in men started to decline from the third decade and continued to decline at a constant rate. However, in women, these parameters remained nearly constant until the fifth decade and then declined at a more rapid rate than that seen in men. Consequently, changes in the buckling ratio, earlier onset, and continuation of increase over the lifetime were observed in men. A relatively later onset with a greater acceleration with aging was observed in women. Taken together, there were obvious gender and age differences in structural trends with age. Bone aging, i.e., bone loss and geometric deterioration, actually begins at a young age, especially in men, and osteoporosis prevention strategies should target not only the elderly but also younger individuals.
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