Evidence map›Paper›PMID 23246741›Full record

ReviewWorld neurosurgery2014

Imaging techniques in spinal cord injury.

Benjamin M Ellingson, Noriko Salamon, Langston T Holly

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. SV2A PET Imaging Detects Severity-Dependent Synaptic Changes After Experimental Traumatic Spinal Cord Injury.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  3. Review
  4. An integrative nomogram based on MRI radiomics and clinical characteristics for prognosis prediction in cervical spinal cord Injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  5. Article
  6. Review
  7. MicroRNAs in spinal cord injury: A narrative review.Frontiers in molecular neuroscience · 2023
    Review
  8. SV2A PET Imaging Is a Noninvasive Marker for the Detection of Spinal Damage in Experimental Models of Spinal Cord Injury.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. [Decompression by mini-open posterior approach assisted with microscope for thoracolumbar burst fracture with severe spinal canal stenosis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin M EllingsonDepartment of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA; Department of Biomedical Physics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA; Department of Bioengineering, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Noriko SalamonDepartment of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Langston T HollyDepartment of Neurosurgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA. Electronic address: lholly@mednet.ucla.edu.
University of California, Los Angeles · US

Funding

Spinal and Cerebral biomarkers for measuring disease progression and prognosis in chronic spinal cord injuryR01NS078494 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ELLINGSON, BENJAMIN M., HOLLY, LANGSTON TYLER · 2012 to 2022
$3.6M
MR Spectroscopy to Explore Spinal Cord Viability in Chronic Spinal Cord InjuryR21NS065419 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOLLY, LANGSTON TYLER · 2009 to 2010
$421k
NINDS NIH HHS R01 NS078494NINDS NIH HHS R21 NS065419
6 · The paper itself

Abstract

backgroundSpinal imaging plays a critical role in the diagnosis, treatment, and rehabilitation of patients with spinal cord injury (SCI). In recent years there has been increasing interest in the development of advanced imaging techniques to provide pertinent microstructural and metabolic information that is not provided by conventional modalities.

methodsThis review details the pathophysiological structural changes that accompany SCI, as well as their imaging correlates. The potential clinical applications of novel spinal cord imaging techniques to SCI are presented.

resultsThere are a variety of novel advanced imaging techniques that are principally focused on the microstructural and/or biochemical function of the spinal cord, and can potentially be applied to traumatic SCI, including diffusion tensor imaging, magnetic resonance spectroscopy, positron emission tomography, single-photon emission computed tomography, and functional magnetic resonance imaging. These techniques are presently in various stages of development, including some whose applications are primarily limited to laboratory investigation, whereas others are being actively used in clinical practice.

conclusionAdvanced imaging of the spinal cord has tremendous potential to provide patient-specific physiological information about the status of cord integrity and health. Advanced spinal cord imaging is still at early stages of development and clinical implementation but is likely to play an increasingly important role in the management of spinal cord health in the foreseeable future.

Indexed as

HumansMagnetic Resonance ImagingNeuroimagingRadiographySpinal CordSpinal Cord InjuriesCordImagingInjurySpinal

Identifiers

PMID23246741
PMCPMC3980138
OpenAlexW2025675613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.